SPO16_YEAST
ID SPO16_YEAST Reviewed; 198 AA.
AC P17122; D3DLA2;
DT 01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1990, sequence version 1.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=Sporulation-specific protein 16;
GN Name=SPO16; OrderedLocusNames=YHR153C;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2188099; DOI=10.1128/mcb.10.6.2809-2819.1990;
RA Malavasic M.J., Elder R.T.;
RT "Complementary transcripts from two genes necessary for normal meiosis in
RT the yeast Saccharomyces cerevisiae.";
RL Mol. Cell. Biol. 10:2809-2819(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8091229; DOI=10.1126/science.8091229;
RA Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z.,
RA Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T.,
RA Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P., Louis E.J.,
RA Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L.,
RA St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P.,
RA Waterston R., Wilson R., Vaudin M.;
RT "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome
RT VIII.";
RL Science 265:2077-2082(1994).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
CC -!- FUNCTION: Necessary for efficient spore formation.
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DR EMBL; M32653; AAA35075.1; -; Genomic_DNA.
DR EMBL; U10397; AAB68989.1; -; Genomic_DNA.
DR EMBL; BK006934; DAA06846.1; -; Genomic_DNA.
DR PIR; A36321; A36321.
DR RefSeq; NP_012023.1; NM_001179284.1.
DR PDB; 6BZF; X-ray; 2.29 A; A/C/E/G=2-198.
DR PDB; 6BZG; X-ray; 2.13 A; A=2-198.
DR PDBsum; 6BZF; -.
DR PDBsum; 6BZG; -.
DR AlphaFoldDB; P17122; -.
DR SMR; P17122; -.
DR BioGRID; 36587; 55.
DR ComplexPortal; CPX-1386; Synapsis initiation complex.
DR ComplexPortal; CPX-5441; SPO16:ZIP2.
DR ComplexPortal; CPX-5442; ZZS complex.
DR IntAct; P17122; 1.
DR STRING; 4932.YHR153C; -.
DR PaxDb; P17122; -.
DR EnsemblFungi; YHR153C_mRNA; YHR153C; YHR153C.
DR GeneID; 856558; -.
DR KEGG; sce:YHR153C; -.
DR SGD; S000001196; SPO16.
DR VEuPathDB; FungiDB:YHR153C; -.
DR eggNOG; ENOG502SDYW; Eukaryota.
DR HOGENOM; CLU_1378842_0_0_1; -.
DR InParanoid; P17122; -.
DR OMA; FWDELIF; -.
DR BioCyc; YEAST:G3O-31188-MON; -.
DR PRO; PR:P17122; -.
DR Proteomes; UP000002311; Chromosome VIII.
DR RNAct; P17122; protein.
DR GO; GO:0000794; C:condensed nuclear chromosome; IC:ComplexPortal.
DR GO; GO:0106069; C:synapsis initiation complex; IC:ComplexPortal.
DR GO; GO:0000217; F:DNA secondary structure binding; IDA:SGD.
DR GO; GO:0030437; P:ascospore formation; IMP:SGD.
DR GO; GO:0007129; P:homologous chromosome pairing at meiosis; IC:ComplexPortal.
DR GO; GO:0035825; P:homologous recombination; IC:ComplexPortal.
DR GO; GO:0033235; P:positive regulation of protein sumoylation; IMP:SGD.
DR GO; GO:0016925; P:protein sumoylation; IC:ComplexPortal.
DR GO; GO:0007131; P:reciprocal meiotic recombination; IC:ComplexPortal.
DR GO; GO:0010520; P:regulation of reciprocal meiotic recombination; IMP:SGD.
DR GO; GO:0090173; P:regulation of synaptonemal complex assembly; IC:ComplexPortal.
DR GO; GO:0007130; P:synaptonemal complex assembly; IMP:SGD.
DR InterPro; IPR043637; Spo16.
DR Pfam; PF19225; Spo16; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Meiosis; Reference proteome; Sporulation.
FT CHAIN 1..198
FT /note="Sporulation-specific protein 16"
FT /id="PRO_0000072136"
FT STRAND 7..14
FT /evidence="ECO:0007829|PDB:6BZG"
FT STRAND 22..29
FT /evidence="ECO:0007829|PDB:6BZG"
FT HELIX 31..39
FT /evidence="ECO:0007829|PDB:6BZG"
FT HELIX 44..67
FT /evidence="ECO:0007829|PDB:6BZG"
FT STRAND 78..85
FT /evidence="ECO:0007829|PDB:6BZG"
FT HELIX 91..104
FT /evidence="ECO:0007829|PDB:6BZG"
FT HELIX 108..112
FT /evidence="ECO:0007829|PDB:6BZG"
FT STRAND 113..119
FT /evidence="ECO:0007829|PDB:6BZG"
FT HELIX 125..131
FT /evidence="ECO:0007829|PDB:6BZG"
FT HELIX 133..143
FT /evidence="ECO:0007829|PDB:6BZG"
FT TURN 144..147
FT /evidence="ECO:0007829|PDB:6BZG"
FT HELIX 150..153
FT /evidence="ECO:0007829|PDB:6BZG"
FT HELIX 157..171
FT /evidence="ECO:0007829|PDB:6BZG"
FT HELIX 176..178
FT /evidence="ECO:0007829|PDB:6BZG"
FT HELIX 179..185
FT /evidence="ECO:0007829|PDB:6BZG"
FT HELIX 189..195
FT /evidence="ECO:0007829|PDB:6BZG"
SQ SEQUENCE 198 AA; 23131 MW; 279AF36EC194E4BC CRC64;
MSEFFWDVQK IQEISNVEEH SVVKCVTVNT SRLISQLNEE LQDEESGVNF IVTQLQLLIN
NVYEKIQKSP GVPAHRSLMI NLNFTRLKFS IAYWDILLER SLDLINGPSK TGARYFITEV
TPVDRSRYVE NNQYFLAFKA NQRLTRNSVD MDEFIDFEIL IKQIIFDLFK KNGIPDQDFE
AILSRFHNLE SLVVAFNE
