SPP11_CAEEL
ID SPP11_CAEEL Reviewed; 394 AA.
AC Q10018;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 06-JUN-2002, sequence version 2.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Saposin-like protein 11;
DE Flags: Precursor;
GN Name=spp-11; ORFNames=T25D10.3;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
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DR EMBL; FO081506; CCD72075.1; -; Genomic_DNA.
DR PIR; T16940; T16940.
DR RefSeq; NP_495291.2; NM_062890.4.
DR AlphaFoldDB; Q10018; -.
DR STRING; 6239.T25D10.3; -.
DR EPD; Q10018; -.
DR PaxDb; Q10018; -.
DR PeptideAtlas; Q10018; -.
DR EnsemblMetazoa; T25D10.3a.1; T25D10.3a.1; WBGene00004996.
DR UCSC; T25D10.3; c. elegans.
DR WormBase; T25D10.3a; CE52758; WBGene00004996; spp-11.
DR eggNOG; ENOG502SG84; Eukaryota.
DR HOGENOM; CLU_700635_0_0_1; -.
DR InParanoid; Q10018; -.
DR OMA; CKHVPFC; -.
DR OrthoDB; 1861806at2759; -.
DR PRO; PR:Q10018; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00004996; Expressed in larva.
DR ExpressionAtlas; Q10018; baseline and differential.
DR InterPro; IPR011001; Saposin-like.
DR InterPro; IPR008139; SaposinB_dom.
DR SMART; SM00741; SapB; 1.
DR SUPFAM; SSF47862; SSF47862; 1.
DR PROSITE; PS50015; SAP_B; 1.
PE 3: Inferred from homology;
KW Disulfide bond; Glycoprotein; Reference proteome; Signal.
FT SIGNAL 1..18
FT /evidence="ECO:0000255"
FT CHAIN 19..394
FT /note="Saposin-like protein 11"
FT /id="PRO_0000031672"
FT DOMAIN 306..394
FT /note="Saposin B-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00415"
FT CARBOHYD 25
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00415"
FT CARBOHYD 272
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00415"
FT DISULFID 310..393
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00415"
FT DISULFID 313..387
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00415"
FT DISULFID 343..359
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00415"
SQ SEQUENCE 394 AA; 43473 MW; FC0F25B58FDB3C12 CRC64;
MSVFRFLLFL SLLVGSNAFV KPQYNVTGQI DSALQRFFGI TLPSLKIPDL LNPDKKRNPP
SVGQLKKTSF PLCNVNLPPI FFTISLFRIK LPNLIPTALP VIKLPTIKIP NILPTLPTIK
VPTIKIPDII PITLPTIKIP EVVPTNLPTV EIPHFIPKTL PTVKIPNIIP TNFPTIETPD
IIPKILPTIK IPEIIPLTLP TVKIPDIIPI TLPTIKIPEI VPTKLPTVEV PDTIPKTLPT
TKIPDIVPIT SPTVKIPQII PTIKIPDIIP KNLSTLGPIK LPTIKLPTLP HILPTKSPKP
TPSHKGNMVC DICEKVIGVL TTRLLEIIQK FRVEADKFLT KLCTSLTSNP KTLTVGTMCV
MFKGNIMDTI FKGFDGLKKN LEPVSFCKHV PFCK