SPP1_ARATH
ID SPP1_ARATH Reviewed; 423 AA.
AC Q9C8J4;
DT 23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 25-MAY-2022, entry version 107.
DE RecName: Full=Probable sucrose-phosphatase 1;
DE Short=AtSPP1;
DE EC=3.1.3.24;
GN Name=SPP1; OrderedLocusNames=At1g51420; ORFNames=F5D21.9;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12559580; DOI=10.1016/s0378-1119(02)01177-0;
RA Lunn J.E.;
RT "Sucrose-phosphatase gene families in plants.";
RL Gene 303:187-196(2003).
CC -!- FUNCTION: Catalyzes the final step of sucrose synthesis. {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + sucrose 6(F)-phosphate = phosphate + sucrose;
CC Xref=Rhea:RHEA:19289, ChEBI:CHEBI:15377, ChEBI:CHEBI:17992,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:57723; EC=3.1.3.24;
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
CC -!- PATHWAY: Glycan biosynthesis; sucrose biosynthesis; sucrose from D-
CC fructose 6-phosphate and UDP-alpha-D-glucose: step 2/2.
CC -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the sucrose phosphatase family. {ECO:0000305}.
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DR EMBL; AC024261; AAG52615.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE32666.1; -; Genomic_DNA.
DR PIR; D96552; D96552.
DR RefSeq; NP_175553.1; NM_104020.3.
DR AlphaFoldDB; Q9C8J4; -.
DR SMR; Q9C8J4; -.
DR STRING; 3702.AT1G51420.1; -.
DR PaxDb; Q9C8J4; -.
DR PRIDE; Q9C8J4; -.
DR ProteomicsDB; 232551; -.
DR EnsemblPlants; AT1G51420.1; AT1G51420.1; AT1G51420.
DR GeneID; 841567; -.
DR Gramene; AT1G51420.1; AT1G51420.1; AT1G51420.
DR KEGG; ath:AT1G51420; -.
DR Araport; AT1G51420; -.
DR TAIR; locus:2033893; AT1G51420.
DR eggNOG; ENOG502S8I4; Eukaryota.
DR HOGENOM; CLU_030534_1_0_1; -.
DR InParanoid; Q9C8J4; -.
DR OMA; VENCDAY; -.
DR PhylomeDB; Q9C8J4; -.
DR UniPathway; UPA00371; UER00546.
DR PRO; PR:Q9C8J4; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C8J4; baseline and differential.
DR Genevisible; Q9C8J4; AT.
DR GO; GO:0000325; C:plant-type vacuole; HDA:TAIR.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0050307; F:sucrose-phosphate phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0005986; P:sucrose biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.1000; -; 1.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR006379; HAD-SF_hydro_IIB.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR013679; SPP_C.
DR InterPro; IPR006380; SPP_N.
DR InterPro; IPR012847; Sucrose_phosphatase_pln/cyn.
DR Pfam; PF05116; S6PP; 1.
DR Pfam; PF08472; S6PP_C; 1.
DR SUPFAM; SSF54427; SSF54427; 1.
DR SUPFAM; SSF56784; SSF56784; 1.
DR TIGRFAMs; TIGR01484; HAD-SF-IIB; 1.
DR TIGRFAMs; TIGR01485; SPP_plant-cyano; 1.
PE 2: Evidence at transcript level;
KW Hydrolase; Magnesium; Reference proteome.
FT CHAIN 1..423
FT /note="Probable sucrose-phosphatase 1"
FT /id="PRO_0000350613"
SQ SEQUENCE 423 AA; 47846 MW; 0C836321EF392CD7 CRC64;
MERLTSPPRL MIVSDLDETM VDHHKDPENL ALLRFNSLWE DAYRHDSLLV FSTGRAQTMY
KKLRKEKPLL TPDVIITSVG TEIAYGNSMV PDDNWVEILN KKWDRGIVQE ETSKFPELTL
QGETEQRPHK LSFNIDKSKV KAVTKELSPR LEKRGVDVKF IFSGGNAFDV LAKGGGKGQA
LAYLLKKLKT EGKLPINTLA CGDSGNDTEL FTIPNVYGVM VSNAQEELLE WYAENAKDNA
NIIHASERCA GGITQAIGHF KLGPNLSPRD VSDFLECKAD NVNPGHEVVK FFLFYERWRR
GEVENCTTYT SSLKASCHPS GVFVHPSGAE KSLRDTIDEL GKYYGDKKGK KFRVWTDQVL
ATDTTPGTWI VKLDKWEQTG DERKCCTTTV KFTSKEGEGF VWEHVQQIWS EETEIKDDSN
WII
