ID   SPP2_CANGA              Reviewed;         169 AA.
AC   Q6FMB1;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Pre-mRNA-splicing factor SPP2;
GN   Name=SPP2; OrderedLocusNames=CAGL0K09504g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in spliceosome maturation and the first step of pre-
CC       mRNA splicing. {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SPP2 family. {ECO:0000305}.
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DR   EMBL; CR380957; CAG61596.1; -; Genomic_DNA.
DR   RefSeq; XP_448633.1; XM_448633.1.
DR   AlphaFoldDB; Q6FMB1; -.
DR   STRING; 5478.XP_448633.1; -.
DR   EnsemblFungi; CAG61596; CAG61596; CAGL0K09504g.
DR   GeneID; 2890235; -.
DR   KEGG; cgr:CAGL0K09504g; -.
DR   CGD; CAL0134945; CAGL0K09504g.
DR   VEuPathDB; FungiDB:CAGL0K09504g; -.
DR   eggNOG; ENOG502S8BR; Eukaryota.
DR   HOGENOM; CLU_110336_0_0_1; -.
DR   InParanoid; Q6FMB1; -.
DR   Proteomes; UP000002428; Chromosome K.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0001671; F:ATPase activator activity; IEA:EnsemblFungi.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:EnsemblFungi.
DR   GO; GO:0032781; P:positive regulation of ATP-dependent activity; IEA:EnsemblFungi.
DR   InterPro; IPR045166; Spp2-like.
DR   InterPro; IPR026822; Spp2/MOS2_G-patch.
DR   PANTHER; PTHR15818; PTHR15818; 1.
DR   Pfam; PF12656; G-patch_2; 1.
PE   3: Inferred from homology;
KW   mRNA processing; mRNA splicing; Nucleus; Reference proteome; Spliceosome.
FT   CHAIN           1..169
FT                   /note="Pre-mRNA-splicing factor SPP2"
FT                   /id="PRO_0000218521"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   169 AA;  19046 MW;  135D90319E5A6C21 CRC64;
     MFSLKLGKNK KKKKVPKGDS ELFGSEASVD DKVSLTQYNY ADEREKEKPK KRKIELATAE
     SETIALKRAK NNIGDDSIVQ ELEALPEKVE DKEYEEMPVE EFGAAMLRGM GWTDENELED
     SKSHSKKLPH EQIHPEGLGI GAKSQEMSNP VSVKDLVNDF MPVKKVPKQ