ID   SPP2_USTMA              Reviewed;         417 AA.
AC   Q4P9X4; A0A0D1DZT9;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Pre-mRNA-splicing factor SPP2;
GN   Name=SPP2; ORFNames=UMAG_03089;
OS   Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=237631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021;
RX   PubMed=17080091; DOI=10.1038/nature05248;
RA   Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA   Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA   Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA   Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA   Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA   Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA   Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA   Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA   Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA   Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA   Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA   Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA   Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA   Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA   Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA   Birren B.W.;
RT   "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT   maydis.";
RL   Nature 444:97-101(2006).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=521 / FGSC 9021;
RA   Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in spliceosome maturation and the first step of pre-
CC       mRNA splicing. {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SPP2 family. {ECO:0000305}.
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DR   EMBL; CM003146; KIS69111.1; -; Genomic_DNA.
DR   RefSeq; XP_011389448.1; XM_011391146.1.
DR   AlphaFoldDB; Q4P9X4; -.
DR   STRING; 5270.UM03089P0; -.
DR   PRIDE; Q4P9X4; -.
DR   EnsemblFungi; KIS69111; KIS69111; UMAG_03089.
DR   GeneID; 23563658; -.
DR   KEGG; uma:UMAG_03089; -.
DR   VEuPathDB; FungiDB:UMAG_03089; -.
DR   eggNOG; ENOG502RZY8; Eukaryota.
DR   HOGENOM; CLU_045413_1_0_1; -.
DR   InParanoid; Q4P9X4; -.
DR   OMA; IDQFGMA; -.
DR   OrthoDB; 1427830at2759; -.
DR   Proteomes; UP000000561; Chromosome 7.
DR   GO; GO:0005681; C:spliceosomal complex; IBA:GO_Central.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   InterPro; IPR000467; G_patch_dom.
DR   InterPro; IPR045166; Spp2-like.
DR   InterPro; IPR026822; Spp2/MOS2_G-patch.
DR   PANTHER; PTHR15818; PTHR15818; 1.
DR   Pfam; PF12656; G-patch_2; 1.
DR   SMART; SM00443; G_patch; 1.
DR   PROSITE; PS50174; G_PATCH; 1.
PE   3: Inferred from homology;
KW   mRNA processing; mRNA splicing; Nucleus; Reference proteome; Spliceosome.
FT   CHAIN           1..417
FT                   /note="Pre-mRNA-splicing factor SPP2"
FT                   /id="PRO_0000218528"
FT   DOMAIN          227..273
FT                   /note="G-patch"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT   REGION          1..70
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          201..221
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          240..417
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..24
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        202..216
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        319..353
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        366..417
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   417 AA;  45533 MW;  30E9D10F8AB2F561 CRC64;
     MAGSLRDRAH KPSTRPRAFD DSDDDDAGLL ASSSSRHEEE IVSFGRDGAK GRGASPVSDA
     PRVIPVTSNL DWRQDRKERL GRASNLQALG PLVSMRRAGA SAVPGLASSS STNDDINIDA
     INTEAQKRGL KLRSSKVTRA DDTPQQLSGD VFDEQTADAS AVPKASADVA GEDAEAIKAL
     LAGQGNDSAG TGGQLIIHQE TESELLQHDI DSRPEAPTLD DYAATPIDQF GMALLRGMGW
     KEGMGAGKGG KGPQQAAEPR KRAALLGLGA KERPTGPLNL SKPSSSSGNL QPKDKRDYKY
     VPVSKSDPRD YSNGRSPSSD HQPREKRPSK SHSTDLPSSH DSRRGDRDDR HARHSRTSHR
     QRSRSPTRSG VHDRDRRHER RRDGRDPERR SHPSSRSDRD RRSECDRDER RSSGHRR