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ABHD8_BOVIN
ID   ABHD8_BOVIN             Reviewed;         432 AA.
AC   Q17QP1;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Protein ABHD8 {ECO:0000305};
DE            EC=3.-.-.-;
DE   AltName: Full=Alpha/beta hydrolase domain-containing protein 8 {ECO:0000305};
DE            Short=Abhydrolase domain-containing protein 8 {ECO:0000250|UniProtKB:Q96I13};
GN   Name=ABHD8 {ECO:0000250|UniProtKB:Q96I13};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Thalamus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. {ECO:0000305}.
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DR   EMBL; BC118251; AAI18252.1; -; mRNA.
DR   RefSeq; NP_001071591.1; NM_001078123.1.
DR   AlphaFoldDB; Q17QP1; -.
DR   SMR; Q17QP1; -.
DR   STRING; 9913.ENSBTAP00000036358; -.
DR   ESTHER; bovin-abhd8; ABHD8.
DR   PaxDb; Q17QP1; -.
DR   PRIDE; Q17QP1; -.
DR   Ensembl; ENSBTAT00000036501; ENSBTAP00000036358; ENSBTAG00000025809.
DR   GeneID; 768306; -.
DR   KEGG; bta:768306; -.
DR   CTD; 79575; -.
DR   VEuPathDB; HostDB:ENSBTAG00000025809; -.
DR   VGNC; VGNC:25504; ABHD8.
DR   eggNOG; KOG2382; Eukaryota.
DR   GeneTree; ENSGT00390000007336; -.
DR   HOGENOM; CLU_057347_0_0_1; -.
DR   InParanoid; Q17QP1; -.
DR   OMA; HCQRRIT; -.
DR   OrthoDB; 729023at2759; -.
DR   TreeFam; TF331708; -.
DR   Proteomes; UP000009136; Chromosome 7.
DR   Bgee; ENSBTAG00000025809; Expressed in retina and 104 other tissues.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; IBA:GO_Central.
DR   GO; GO:0042171; F:lysophosphatidic acid acyltransferase activity; IBA:GO_Central.
DR   GO; GO:0055088; P:lipid homeostasis; IBA:GO_Central.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; IBA:GO_Central.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR000639; Epox_hydrolase-like.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   PRINTS; PR00111; ABHYDROLASE.
DR   PRINTS; PR00412; EPOXHYDRLASE.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..432
FT                   /note="Protein ABHD8"
FT                   /id="PRO_0000281381"
FT   DOMAIN          170..272
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000255"
FT   REGION          47..69
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          121..149
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        245
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        363
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        391
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   432 AA;  46833 MW;  F6C7412E397E6FB0 CRC64;
     MLTGVTDGIF CCLLGAPPNA VGPLESVESS DGYTFVEVKP GRVLRVKHAG PAPAPTPPPP
     LSDAAQGDQS GLVRCQRRIT VYRNGRLLVE NLGRAPRADL LHGQNGSGEP PAALEVELAD
     PAGSDGRSVP GSAGSGSGGR RRRARRPKRT IHIDCEKRIT SCKGAQADVV LFFIHGVGGS
     LAIWKEQLDF FVRLGYEVVA PDLAGHGASS APQVAAAYTF YALAEDMRAI FKRYAKKRNV
     LIGHSYGVSF CTFLAHEYPD LVHKVIMING GGPTALEPSL CSVFNMPTCV LHCLSPCLAW
     SFLKAGFARQ GAKEKQLLKE GNAFNVSSFV LRAMMSGQYW PEGDEVYHAE LTVPVLLVHG
     MHDKFVPVEE DQRMAEILLL AFLKLIDEGS HMVMLECPET VNTLLHEFLL WEPEPSPKAL
     PEPLPAPPEE KK
 
 
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