ID   SPRTL_STRP3             Reviewed;         145 AA.
AC   P0DF74; Q8K886;
DT   27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT   27-JUL-2011, sequence version 1.
DT   03-AUG-2022, entry version 39.
DE   RecName: Full=Protein SprT-like {ECO:0000255|HAMAP-Rule:MF_00745};
GN   OrderedLocusNames=SpyM3_0410;
OS   Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=198466;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-595 / MGAS315;
RX   PubMed=12122206; DOI=10.1073/pnas.152298499;
RA   Beres S.B., Sylva G.L., Barbian K.D., Lei B., Hoff J.S., Mammarella N.D.,
RA   Liu M.-Y., Smoot J.C., Porcella S.F., Parkins L.D., Campbell D.S.,
RA   Smith T.M., McCormick J.K., Leung D.Y.M., Schlievert P.M., Musser J.M.;
RT   "Genome sequence of a serotype M3 strain of group A Streptococcus: phage-
RT   encoded toxins, the high-virulence phenotype, and clone emergence.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:10078-10083(2002).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00745};
CC       Note=Binds 1 zinc ion. {ECO:0000255|HAMAP-Rule:MF_00745};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00745}.
CC   -!- SIMILARITY: Belongs to the SprT family. {ECO:0000255|HAMAP-
CC       Rule:MF_00745}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAM79017.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE014074; AAM79017.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_002990585.1; NC_004070.1.
DR   AlphaFoldDB; P0DF74; -.
DR   EnsemblBacteria; AAM79017; AAM79017; SpyM3_0410.
DR   GeneID; 57852294; -.
DR   KEGG; spg:SpyM3_0410; -.
DR   HOGENOM; CLU_123820_0_0_9; -.
DR   OMA; LVHYHLH; -.
DR   Proteomes; UP000000564; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051716; P:cellular response to stimulus; IEA:UniProt.
DR   HAMAP; MF_00745; SprT_like; 1.
DR   InterPro; IPR006640; SprT-like_domain.
DR   InterPro; IPR023524; Uncharacterised_SprT-like.
DR   Pfam; PF10263; SprT-like; 1.
DR   SMART; SM00731; SprT; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Metal-binding; Zinc.
FT   CHAIN           1..145
FT                   /note="Protein SprT-like"
FT                   /id="PRO_0000213311"
FT   DOMAIN          4..140
FT                   /note="SprT-like"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00745"
FT   ACT_SITE        65
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00745"
FT   BINDING         64
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00745"
FT   BINDING         68
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00745"
SQ   SEQUENCE   145 AA;  17229 MW;  06129080E520E5D1 CRC64;
     MTLTNYVQEV SLADFGKPFH HKAYWNKRLK TTGGRFFPKD GHLDFNPRML EEHGELIFRK
     IVRHELCHYH LYFEGRGYHH KDRDFKDLLA QVNGLRYVPT SSKSKTNHHY SCQTCGQVYQ
     RKRRINLAKY VCGNCHGKLM EKNQS