SPRT_ECO24
ID SPRT_ECO24 Reviewed; 165 AA.
AC A7ZR67;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 23-OCT-2007, sequence version 1.
DT 03-AUG-2022, entry version 63.
DE RecName: Full=Protein SprT {ECO:0000255|HAMAP-Rule:MF_00746};
GN Name=sprT {ECO:0000255|HAMAP-Rule:MF_00746};
GN OrderedLocusNames=EcE24377A_3287;
OS Escherichia coli O139:H28 (strain E24377A / ETEC).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=331111;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E24377A / ETEC;
RX PubMed=18676672; DOI=10.1128/jb.00619-08;
RA Rasko D.A., Rosovitz M.J., Myers G.S.A., Mongodin E.F., Fricke W.F.,
RA Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R.,
RA Henderson I.R., Sperandio V., Ravel J.;
RT "The pangenome structure of Escherichia coli: comparative genomic analysis
RT of E. coli commensal and pathogenic isolates.";
RL J. Bacteriol. 190:6881-6893(2008).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00746};
CC Note=Binds 1 zinc ion. {ECO:0000255|HAMAP-Rule:MF_00746};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00746}.
CC -!- SIMILARITY: Belongs to the SprT family. {ECO:0000255|HAMAP-
CC Rule:MF_00746}.
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DR EMBL; CP000800; ABV20007.1; -; Genomic_DNA.
DR RefSeq; WP_001495390.1; NC_009801.1.
DR AlphaFoldDB; A7ZR67; -.
DR EnsemblBacteria; ABV20007; ABV20007; EcE24377A_3287.
DR KEGG; ecw:EcE24377A_3287; -.
DR HOGENOM; CLU_113336_0_1_6; -.
DR OMA; QPHGEEW; -.
DR Proteomes; UP000001122; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0051716; P:cellular response to stimulus; IEA:UniProt.
DR HAMAP; MF_00746; SprT; 1.
DR InterPro; IPR006640; SprT-like_domain.
DR InterPro; IPR035240; SprT_Zn_ribbon.
DR InterPro; IPR023483; Uncharacterised_SprT.
DR Pfam; PF10263; SprT-like; 1.
DR Pfam; PF17283; Zn_ribbon_SprT; 1.
DR SMART; SM00731; SprT; 1.
DR PROSITE; PS00142; ZINC_PROTEASE; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Metal-binding; Zinc.
FT CHAIN 1..165
FT /note="Protein SprT"
FT /id="PRO_1000062175"
FT DOMAIN 20..163
FT /note="SprT-like"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00746"
FT ACT_SITE 79
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00746"
FT BINDING 78
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00746"
FT BINDING 82
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00746"
SQ SEQUENCE 165 AA; 19351 MW; 0A1513992BCC2AA9 CRC64;
MKTSRLPIAI QQAVMRRLRE KLTQANLKLG RNYPEPKLSY TQRGTSAGTA WLESYEIRLN
PVLLLENSEA FIEEVVPHEL AHLLVWKHFG RVAPHGKEWK WMMESVLGVP ARRTHQFELQ
SVRRNTFPYR CKCQEHQLTV RRHNRVVRGE AVYRCVHCGE QLVAK