SPRT_ECO57
ID SPRT_ECO57 Reviewed; 165 AA.
AC Q8XCW6;
DT 16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Protein SprT;
GN Name=sprT; OrderedLocusNames=Z4289, ECs3820;
OS Escherichia coli O157:H7.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83334;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX PubMed=11206551; DOI=10.1038/35054089;
RA Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA Blattner F.R.;
RT "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL Nature 409:529-533(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000305};
CC Note=Binds 1 zinc ion. {ECO:0000305};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the SprT family. {ECO:0000305}.
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DR EMBL; AE005174; AAG58075.1; -; Genomic_DNA.
DR EMBL; BA000007; BAB37243.1; -; Genomic_DNA.
DR PIR; D91106; D91106.
DR PIR; G85951; G85951.
DR RefSeq; NP_311847.1; NC_002695.1.
DR RefSeq; WP_001303653.1; NZ_SEKU01000002.1.
DR AlphaFoldDB; Q8XCW6; -.
DR SMR; Q8XCW6; -.
DR STRING; 155864.EDL933_4155; -.
DR EnsemblBacteria; AAG58075; AAG58075; Z4289.
DR EnsemblBacteria; BAB37243; BAB37243; ECs_3820.
DR GeneID; 916358; -.
DR KEGG; ece:Z4289; -.
DR KEGG; ecs:ECs_3820; -.
DR PATRIC; fig|386585.9.peg.3986; -.
DR eggNOG; COG3091; Bacteria.
DR HOGENOM; CLU_113336_0_1_6; -.
DR OMA; QPHGEEW; -.
DR Proteomes; UP000000558; Chromosome.
DR Proteomes; UP000002519; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0051716; P:cellular response to stimulus; IEA:UniProt.
DR HAMAP; MF_00746; SprT; 1.
DR InterPro; IPR006640; SprT-like_domain.
DR InterPro; IPR035240; SprT_Zn_ribbon.
DR InterPro; IPR023483; Uncharacterised_SprT.
DR Pfam; PF10263; SprT-like; 1.
DR Pfam; PF17283; Zn_ribbon_SprT; 1.
DR SMART; SM00731; SprT; 1.
DR PROSITE; PS00142; ZINC_PROTEASE; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Metal-binding; Reference proteome; Zinc.
FT CHAIN 1..165
FT /note="Protein SprT"
FT /id="PRO_0000213267"
FT DOMAIN 20..163
FT /note="SprT-like"
FT ACT_SITE 79
FT /evidence="ECO:0000255"
FT BINDING 78
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255"
FT BINDING 82
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255"
SQ SEQUENCE 165 AA; 19252 MW; E414A3989BD721A9 CRC64;
MKTSRLPIAI QQAVMRRLRE KLAQANLKLG RNYPEPKLSY TQRGTSAGTA WLESYEIRLN
PVLLLENSEA FIEEVVPHEL AHLLVWKHFG RVAPHGKEWK WMMESVLGVP ARRTHQFELQ
SVRRNTFPYS CKCQEHQLTV RRHNRVVRGE AVYRCVHCGE QLVAK