ID   SPRT_ECOLI              Reviewed;         165 AA.
AC   P39902; Q2M9P9;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 139.
DE   RecName: Full=Protein SprT;
GN   Name=sprT; Synonyms=yggI; OrderedLocusNames=b2944, JW2911;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Utsumi R., Suzuki T.;
RT   "A newly identified gene sprT which is involved in bolA gene expression.";
RL   Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Roberts P.E.;
RL   Thesis (1992), University of Cambridge, United Kingdom.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 70-165.
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=8113204; DOI=10.1128/jb.176.5.1550-1551.1994;
RA   Jekel M., Wackernagel W.;
RT   "Location of the endA gene coding for endonuclease I on the physical map of
RT   the Escherichia coli K-12 chromosome.";
RL   J. Bacteriol. 176:1550-1551(1994).
RN   [6]
RP   IDENTIFICATION.
RX   PubMed=7984428; DOI=10.1093/nar/22.22.4756;
RA   Borodovsky M., Rudd K.E., Koonin E.V.;
RT   "Intrinsic and extrinsic approaches for detecting genes in a bacterial
RT   genome.";
RL   Nucleic Acids Res. 22:4756-4767(1994).
CC   -!- FUNCTION: Involved in bolA gene expression at the stationary phase.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000305};
CC       Note=Binds 1 zinc ion. {ECO:0000305};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the SprT family. {ECO:0000305}.
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DR   EMBL; D83644; BAA12021.1; -; Genomic_DNA.
DR   EMBL; U28377; AAA69111.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC75981.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77007.1; -; Genomic_DNA.
DR   EMBL; X65169; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; G65079; G65079.
DR   RefSeq; NP_417419.1; NC_000913.3.
DR   RefSeq; WP_001300769.1; NZ_SSUV01000019.1.
DR   AlphaFoldDB; P39902; -.
DR   BioGRID; 4259531; 50.
DR   IntAct; P39902; 7.
DR   STRING; 511145.b2944; -.
DR   PaxDb; P39902; -.
DR   PRIDE; P39902; -.
DR   EnsemblBacteria; AAC75981; AAC75981; b2944.
DR   EnsemblBacteria; BAE77007; BAE77007; BAE77007.
DR   GeneID; 947443; -.
DR   KEGG; ecj:JW2911; -.
DR   KEGG; eco:b2944; -.
DR   PATRIC; fig|511145.12.peg.3037; -.
DR   EchoBASE; EB2043; -.
DR   eggNOG; COG3091; Bacteria.
DR   HOGENOM; CLU_113336_0_1_6; -.
DR   InParanoid; P39902; -.
DR   OMA; QPHGEEW; -.
DR   PhylomeDB; P39902; -.
DR   BioCyc; EcoCyc:EG12122-MON; -.
DR   PRO; PR:P39902; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051716; P:cellular response to stimulus; IEA:UniProt.
DR   HAMAP; MF_00746; SprT; 1.
DR   InterPro; IPR006640; SprT-like_domain.
DR   InterPro; IPR035240; SprT_Zn_ribbon.
DR   InterPro; IPR023483; Uncharacterised_SprT.
DR   Pfam; PF10263; SprT-like; 1.
DR   Pfam; PF17283; Zn_ribbon_SprT; 1.
DR   SMART; SM00731; SprT; 1.
DR   PROSITE; PS00142; ZINC_PROTEASE; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Metal-binding; Reference proteome; Zinc.
FT   CHAIN           1..165
FT                   /note="Protein SprT"
FT                   /id="PRO_0000213266"
FT   DOMAIN          20..163
FT                   /note="SprT-like"
FT   ACT_SITE        79
FT                   /evidence="ECO:0000255"
FT   BINDING         78
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255"
FT   BINDING         82
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   165 AA;  19348 MW;  F5E4A3992DD091B4 CRC64;
     MKTSRLPIAI QQAVMRRLRE KLAQANLKLG RNYPEPKLSY TQRGTSAGTA WLESYEIRLN
     PVLLLENSEA FIEEVVPHEL AHLLVWKHFG RVAPHGKEWK WMMENVLGVP ARRTHQFELQ
     SVRRNTFPYR CKCQEHQLTV RRHNRVVRGE AVYRCVHCGE QLVAK