ID   ABHD8_MACFA             Reviewed;         440 AA.
AC   Q4R584;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 55.
DE   RecName: Full=Protein ABHD8 {ECO:0000305};
DE            EC=3.-.-.-;
DE   AltName: Full=Alpha/beta hydrolase domain-containing protein 8 {ECO:0000305};
DE            Short=Abhydrolase domain-containing protein 8 {ECO:0000250|UniProtKB:Q96I13};
GN   Name=ABHD8 {ECO:0000250|UniProtKB:Q96I13}; ORFNames=QccE-15065;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. {ECO:0000305}.
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DR   EMBL; AB169660; BAE01741.1; -; mRNA.
DR   RefSeq; NP_001306273.1; NM_001319344.1.
DR   AlphaFoldDB; Q4R584; -.
DR   SMR; Q4R584; -.
DR   STRING; 9541.XP_005588430.1; -.
DR   ESTHER; macfa-q4r584; ABHD8.
DR   GeneID; 102125699; -.
DR   CTD; 79575; -.
DR   eggNOG; KOG2382; Eukaryota.
DR   Proteomes; UP000233100; Unplaced.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR000639; Epox_hydrolase-like.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   PRINTS; PR00111; ABHYDROLASE.
DR   PRINTS; PR00412; EPOXHYDRLASE.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..440
FT                   /note="Protein ABHD8"
FT                   /id="PRO_0000281383"
FT   DOMAIN          178..280
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000255"
FT   REGION          123..158
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        253
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        371
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        399
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   440 AA;  47426 MW;  E4FB93FB4D10BDBE CRC64;
     MLTGVTDGIF CCLLGTPPNA VGPLESVESS DGYTFVEVKP GRVLRVKHAG PAPASAAPPP
     LSASSDAAQG DLSGLVRCQR RITVYRNGRL LVENLGRAPR ADLLHGQNGS GEPPAALEME
     LADPAGSDGR SAPGSGSGSG SGSGSGGRRR RARRPKRTIH IDCEKRITSC KGAQADVVLF
     FIHGVGGSLA IWKEQLDFFV RLGYEVVAPD LAGHGASSAP QVAAAYTFYA LAEDMRAIFK
     RYAKKRNVLI GHSYGVSFCT FLAHEYPDLV HKVIMINGGG PTALEPSFCS IFNMPTCVLH
     CLSPCLAWSF LKAGFARQGA KEKQLLKEGN AFNVSSFVLR AMMSGQYWPE GDEVYHAELT
     VPVLLVHGMH DKFVPVEEDQ RMAEILLLAF LKLIDEGSHM VMLECPETVN TLLHEFLLWE
     PEPSPKALPE PLPAPPEDKK