ID   SPRT_YERPE              Reviewed;         170 AA.
AC   Q8ZHG6; Q0WIA9; Q8CZV7;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Protein SprT;
GN   Name=sprT; OrderedLocusNames=YPO0932, y3315, YP_3511;
OS   Yersinia pestis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 / Biovar Orientalis;
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA   Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA   Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA   Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KIM10+ / Biovar Mediaevalis;
RX   PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA   Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA   Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA   Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA   Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT   "Genome sequence of Yersinia pestis KIM.";
RL   J. Bacteriol. 184:4601-4611(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis;
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA   Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA   Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000305};
CC       Note=Binds 1 zinc ion. {ECO:0000305};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the SprT family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAM86865.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AAS63665.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AL590842; CAL19598.1; -; Genomic_DNA.
DR   EMBL; AE009952; AAM86865.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AE017042; AAS63665.1; ALT_INIT; Genomic_DNA.
DR   PIR; AD0114; AD0114.
DR   RefSeq; WP_002228059.1; NZ_UHIZ01000001.1.
DR   RefSeq; YP_002345979.1; NC_003143.1.
DR   AlphaFoldDB; Q8ZHG6; -.
DR   SMR; Q8ZHG6; -.
DR   STRING; 214092.YPO0932; -.
DR   PaxDb; Q8ZHG6; -.
DR   DNASU; 1148262; -.
DR   EnsemblBacteria; AAM86865; AAM86865; y3315.
DR   EnsemblBacteria; AAS63665; AAS63665; YP_3511.
DR   GeneID; 57973709; -.
DR   KEGG; ype:YPO0932; -.
DR   KEGG; ypk:y3315; -.
DR   KEGG; ypl:CH46_4215; -.
DR   KEGG; ypm:YP_3511; -.
DR   KEGG; ypv:BZ15_2643; -.
DR   KEGG; ypw:CH59_934; -.
DR   PATRIC; fig|214092.21.peg.1209; -.
DR   eggNOG; COG3091; Bacteria.
DR   HOGENOM; CLU_113336_0_1_6; -.
DR   Proteomes; UP000000815; Chromosome.
DR   Proteomes; UP000001019; Chromosome.
DR   Proteomes; UP000002490; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051716; P:cellular response to stimulus; IEA:UniProt.
DR   HAMAP; MF_00746; SprT; 1.
DR   InterPro; IPR006640; SprT-like_domain.
DR   InterPro; IPR035240; SprT_Zn_ribbon.
DR   InterPro; IPR023483; Uncharacterised_SprT.
DR   Pfam; PF10263; SprT-like; 1.
DR   Pfam; PF17283; Zn_ribbon_SprT; 1.
DR   SMART; SM00731; SprT; 1.
DR   PROSITE; PS00142; ZINC_PROTEASE; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Metal-binding; Reference proteome; Zinc.
FT   CHAIN           1..170
FT                   /note="Protein SprT"
FT                   /id="PRO_0000213284"
FT   DOMAIN          22..165
FT                   /note="SprT-like"
FT   ACT_SITE        79
FT                   /evidence="ECO:0000255"
FT   BINDING         78
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255"
FT   BINDING         82
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        137
FT                   /note="S -> A (in Ref. 2 and 3)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   170 AA;  19923 MW;  5C172226B3962FB0 CRC64;
     MSTLRIPIAL QQAVMQCLRH YLQLANQHLG TAYPEPKVNY HQRGTNAGSA YLQSFEIRLN
     PVLLLENKQP FIDEVVPHEL AHLLVYRQFG RVAPHGKEWR WMMEQVLKVP ASRTHQFEVA
     SVRSKTFNYQ CKCQQHSLTI RRHNKVLRGE SEYRCRQCGE KLQFITINPD