ID   SPRY3_PONAB             Reviewed;         442 AA.
AC   Q5RBR6;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=SPRY domain-containing protein 3;
GN   Name=SPRYD3;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CR858569; CAH90794.1; -; mRNA.
DR   RefSeq; NP_001125451.1; NM_001131979.1.
DR   AlphaFoldDB; Q5RBR6; -.
DR   SMR; Q5RBR6; -.
DR   STRING; 9601.ENSPPYP00000005208; -.
DR   GeneID; 100433323; -.
DR   KEGG; pon:100433323; -.
DR   CTD; 84926; -.
DR   eggNOG; KOG1477; Eukaryota.
DR   InParanoid; Q5RBR6; -.
DR   OrthoDB; 1106989at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   CDD; cd12908; SPRYD3; 2.
DR   Gene3D; 2.60.120.920; -; 2.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR003877; SPRY_dom.
DR   InterPro; IPR035783; SPRYD3_SPRY.
DR   Pfam; PF00622; SPRY; 2.
DR   SMART; SM00449; SPRY; 2.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   PROSITE; PS50188; B302_SPRY; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..442
FT                   /note="SPRY domain-containing protein 3"
FT                   /id="PRO_0000240855"
FT   DOMAIN          17..204
FT                   /note="B30.2/SPRY"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00548"
FT   REGION          371..394
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        371..388
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   442 AA;  49738 MW;  3E818EEEA413AFA2 CRC64;
     MRRTRRPRFV LMNKMDDLNL HYRFLNWRRR IREIREVRAF RYQERFKHIL VDGDTLSYHG
     NSGEVGCYVA SRPLTKDSNY FEVSIVDSGV RGTIAVGLVP QYYSLDHQPG WLPDSVAYHA
     DDGKLYNGRA KGRQFGSKCN SGDRIGCGIE PVSFDVQTAQ IFFTKNGKRV GSTIMPMSPD
     GLFPAVGMHS LGEEVRLHLN AELGREDDSV MMVDSYEDEW GRLHDVRVCG TLLEYLGKGK
     SIVDVGLAQA RHPLSTRSHY FEVEIVDPGE KCYIALGLAR KDYPKNRHPG WSRGSVAYHA
     DDGKIFHGSG VGDPFEPRCY KGDIMGCGIM FPRDYILDSE GDSDDSCDTV ILSPTARAAR
     NVRNVMYLHQ EGEEEEEEEE EEEDGEEIEP EHEGRKVVVF FTRNGKIIGK KDAVVPSGGF
     FPTIGMLSCG EKVKVDLHPL SG