ID   SPSA3_ORYSJ             Reviewed;         977 AA.
AC   Q67WN8; Q0DAM8;
DT   19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Probable sucrose-phosphate synthase 3;
DE            EC=2.4.1.14;
DE   AltName: Full=Sucrose phosphate synthase 3F;
DE            Short=OsSPS3F;
DE   AltName: Full=UDP-glucose-fructose-phosphate glucosyltransferase;
GN   Name=SPS3; Synonyms=SPS6; OrderedLocusNames=Os06g0643800, LOC_Os06g43630;
GN   ORFNames=P0017B12.4, P0416A11.37;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   GENE FAMILY.
RX   PubMed=16876912; DOI=10.1016/j.jplph.2006.04.014;
RA   Lutfiyya L.L., Xu N., D'Ordine R.L., Morrell J.A., Miller P.W., Duff S.M.;
RT   "Phylogenetic and expression analysis of sucrose phosphate synthase
RT   isozymes in plants.";
RL   J. Plant Physiol. 164:923-933(2007).
RN   [5]
RP   TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, AND INDUCTION.
RX   PubMed=21683881; DOI=10.1016/j.plantsci.2011.04.019;
RA   Okamura M., Aoki N., Hirose T., Yonekura M., Ohto C., Ohsugi R.;
RT   "Tissue specificity and diurnal change in gene expression of the sucrose
RT   phosphate synthase gene family in rice.";
RL   Plant Sci. 181:159-166(2011).
CC   -!- FUNCTION: Plays a role in photosynthetic sucrose synthesis by
CC       catalyzing the rate-limiting step of sucrose biosynthesis from UDP-
CC       glucose and fructose- 6-phosphate. Involved in the regulation of carbon
CC       partitioning in the leaves of plants. May regulate the synthesis of
CC       sucrose and therefore play a major role as a limiting factor in the
CC       export of photoassimilates out of the leaf. Plays a role for sucrose
CC       availability that is essential for plant growth and fiber elongation
CC       (By similarity). {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=beta-D-fructose 6-phosphate + UDP-alpha-D-glucose = H(+) +
CC         sucrose 6(F)-phosphate + UDP; Xref=Rhea:RHEA:22172,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:57634, ChEBI:CHEBI:57723,
CC         ChEBI:CHEBI:58223, ChEBI:CHEBI:58885; EC=2.4.1.14;
CC   -!- ACTIVITY REGULATION: Activity is regulated by phosphorylation and
CC       moderated by concentration of metabolites and light. {ECO:0000250}.
CC   -!- PATHWAY: Glycan biosynthesis; sucrose biosynthesis; sucrose from D-
CC       fructose 6-phosphate and UDP-alpha-D-glucose: step 1/2.
CC   -!- SUBUNIT: Homodimer or homotetramer. {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed in germinating seeds.
CC       {ECO:0000269|PubMed:21683881}.
CC   -!- DEVELOPMENTAL STAGE: Esoxpressed in source leaves and sink leaves.
CC       {ECO:0000269|PubMed:21683881}.
CC   -!- INDUCTION: Circadian-regulated, with the highest expression 3 hours
CC       after the beginning of light period (in 14 hours light/10 hours dark
CC       cycle). {ECO:0000269|PubMed:21683881}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAF20095.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AP003523; BAD37372.1; -; Genomic_DNA.
DR   EMBL; AP003568; BAD37428.1; -; Genomic_DNA.
DR   EMBL; AP008212; BAF20095.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014962; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_015643380.1; XM_015787894.1.
DR   AlphaFoldDB; Q67WN8; -.
DR   SMR; Q67WN8; -.
DR   STRING; 4530.OS06T0643800-01; -.
DR   CAZy; GT4; Glycosyltransferase Family 4.
DR   PaxDb; Q67WN8; -.
DR   PRIDE; Q67WN8; -.
DR   GeneID; 4341642; -.
DR   KEGG; osa:4341642; -.
DR   eggNOG; KOG0853; Eukaryota.
DR   InParanoid; Q67WN8; -.
DR   OrthoDB; 101620at2759; -.
DR   BRENDA; 2.4.1.14; 8948.
DR   PlantReactome; R-OSA-1119465; Sucrose biosynthesis.
DR   UniPathway; UPA00371; UER00545.
DR   Proteomes; UP000000763; Chromosome 6.
DR   Proteomes; UP000059680; Chromosome 6.
DR   GO; GO:0016157; F:sucrose synthase activity; IEA:InterPro.
DR   GO; GO:0046524; F:sucrose-phosphate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005986; P:sucrose biosynthetic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd16419; HAD_SPS; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR006380; SPP_N.
DR   InterPro; IPR044161; SPS.
DR   InterPro; IPR035659; SPS_C.
DR   InterPro; IPR012819; SPS_pln.
DR   InterPro; IPR000368; Sucrose_synth.
DR   PANTHER; PTHR46039; PTHR46039; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   Pfam; PF05116; S6PP; 1.
DR   Pfam; PF00862; Sucrose_synth; 1.
DR   TIGRFAMs; TIGR02468; sucrsPsyn_pln; 1.
PE   2: Evidence at transcript level;
KW   Glycosyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..977
FT                   /note="Probable sucrose-phosphate synthase 3"
FT                   /id="PRO_0000413642"
FT   REGION          124..159
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   977 AA;  109462 MW;  6D6C96A32E37E814 CRC64;
     MYGNDNWINS YLDAILDAGK GAAASASASA VGGGGGAGDR PSLLLRERGH FSPARYFVEE
     VITGYDETDL YKTWLRANAM RSPQEKNTRL ENMTWRIWNL ARKKKELEKE EANRLLKRRL
     ETERPRVETT SDMSEDLFEG EKGEDAGDPS VAYGDSTTGN TPRISSVDKL YIVLISLHGL
     VRGENMELGR DSDTGGQVKY VVELAKALSS CPGVYRVDLF TRQILAPNFD RSYGEPVEPL
     ASTSFKNFKQ ERGENSGAYI IRIPFGPKDK YLAKEHLWPF IQEFVDGALS HIVKMSRAIG
     EEISCGHPAW PAVIHGHYAS AGVAAALLSG ALNVPMVFTG HFLGKDKLEE LLKQGRQTRE
     QINMTYKIMC RIEAEELALD ASEIVIASTR QEIEEQWNLY DGFEVILARK LRARVKRGAN
     CYGRYMPRMV IIPPGVEFGH MIHDFDMDGE EDGPSPASED PSIWSEIMRF FTNPRKPMIL
     AVARPYPEKN ITTLVKAFGE CRPLRELANL TLIMGNREAI SKMHNMSAAV LTSVLTLIDE
     YDLYGQVAYP KRHKHSEVPD IYRLAVRTKG AFVNVPYFEQ FGVTLIEAAM HGLPVIATKN
     GAPVEIHQVL DNGLLVDPHD QHAIADALYK LLSEKQLWSK CRENGLKNIH QFSWPEHCKN
     YLSRISTLGP RHPAFASNED RIKAPIKGRK HVTVIAVDSV SKEDLIRIVR NSIEAARKEN
     LSGSTGFVLS TSLTIGEIHS LLMSAGMLPT DFDAFICNSG SDLYYPSCTG DTPSNSRVTF
     ALDRSYQSHI EYHWGGEGLR KYLVKWASSV VERRGRIEKQ VIFEDPEHSS TYCLAFKVVN
     PNHLPPLKEL QKLMRIQSLR CHALYNHGAT RLSVIPIHAS RSKALRYLSV RWGIELQNVV
     VLVGETGDSD YEELFGGLHK TVILKGEFNT SANRIHSVRR YPLQDVVALD SPNIIGIEGY
     GTDDMRSALK QLDIRAQ