ID   SPT19_BOVIN             Reviewed;         154 AA.
AC   Q3SZQ3;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Spermatogenesis-associated protein 19, mitochondrial;
DE   Flags: Precursor;
GN   Name=SPATA19;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Testis;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential for sperm motility and male fertility (By
CC       similarity). Plays an important role in sperm motility by regulating
CC       the organization and function of the mitochondria and is also required
CC       for correct sperm midpiece assembly (By similarity).
CC       {ECO:0000250|UniProtKB:Q9DAQ9}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane
CC       {ECO:0000250|UniProtKB:Q9DAQ9}. Mitochondrion
CC       {ECO:0000250|UniProtKB:Q9DAQ9}. Cell projection, cilium, flagellum
CC       {ECO:0000250|UniProtKB:Q9DAQ9}. Note=Localizes to the midpiece of the
CC       sperm flagellum. {ECO:0000250|UniProtKB:Q9DAQ9}.
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DR   EMBL; BC102751; AAI02752.1; -; mRNA.
DR   RefSeq; NP_001069966.1; NM_001076498.2.
DR   AlphaFoldDB; Q3SZQ3; -.
DR   SMR; Q3SZQ3; -.
DR   STRING; 9913.ENSBTAP00000019506; -.
DR   PaxDb; Q3SZQ3; -.
DR   Ensembl; ENSBTAT00000019506; ENSBTAP00000019506; ENSBTAG00000014651.
DR   GeneID; 618276; -.
DR   KEGG; bta:618276; -.
DR   CTD; 219938; -.
DR   VEuPathDB; HostDB:ENSBTAG00000014651; -.
DR   VGNC; VGNC:35177; SPATA19.
DR   eggNOG; ENOG502SAUZ; Eukaryota.
DR   GeneTree; ENSGT00390000002749; -.
DR   HOGENOM; CLU_149699_0_0_1; -.
DR   InParanoid; Q3SZQ3; -.
DR   OMA; EHWLKKT; -.
DR   OrthoDB; 1465928at2759; -.
DR   TreeFam; TF337965; -.
DR   Proteomes; UP000009136; Chromosome 29.
DR   Bgee; ENSBTAG00000014651; Expressed in semen and 16 other tissues.
DR   GO; GO:0005741; C:mitochondrial outer membrane; ISS:UniProtKB.
DR   GO; GO:0036126; C:sperm flagellum; ISS:UniProtKB.
DR   GO; GO:0097225; C:sperm midpiece; ISS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030382; P:sperm mitochondrion organization; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   InterPro; IPR028219; SPATA19.
DR   PANTHER; PTHR36468; PTHR36468; 1.
DR   Pfam; PF15212; SPATA19; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium; Developmental protein; Differentiation; Flagellum;
KW   Membrane; Mitochondrion; Mitochondrion outer membrane; Phosphoprotein;
KW   Reference proteome; Spermatogenesis; Transit peptide.
FT   TRANSIT         1..24
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..154
FT                   /note="Spermatogenesis-associated protein 19,
FT                   mitochondrial"
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000251608"
FT   MOD_RES         26
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q920Q3"
FT   MOD_RES         116
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q920Q3"
SQ   SEQUENCE   154 AA;  17899 MW;  E0F999FE88373950 CRC64;
     MIITTWIVYI LARKGAGLPF PPKVSSDVEV TETEAVSVVQ HWLKKTEEEA SQEIKEKMST
     NFPPMQGQDV HVTRDVVKHH LSKSGLLANQ SQEVLEERTR IQFIRWSHTR IFQVPSEARN
     EAMRDRIEQV RRSICHLSDE ISQELRNRNS YSEC