SPT20_DICDI
ID SPT20_DICDI Reviewed; 1402 AA.
AC Q54VY3;
DT 14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 61.
DE RecName: Full=Transcription factor SPT20 homolog;
GN ORFNames=DDB_G0280065;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SIMILARITY: Belongs to the SPT20 family. {ECO:0000305}.
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DR EMBL; AAFI02000035; EAL67259.1; -; Genomic_DNA.
DR RefSeq; XP_641222.1; XM_636130.1.
DR AlphaFoldDB; Q54VY3; -.
DR STRING; 44689.DDB0206355; -.
DR PaxDb; Q54VY3; -.
DR PRIDE; Q54VY3; -.
DR EnsemblProtists; EAL67259; EAL67259; DDB_G0280065.
DR GeneID; 8622353; -.
DR KEGG; ddi:DDB_G0280065; -.
DR dictyBase; DDB_G0280065; -.
DR eggNOG; ENOG502RHMF; Eukaryota.
DR HOGENOM; CLU_254259_0_0_1; -.
DR InParanoid; Q54VY3; -.
DR OMA; TSHAHEC; -.
DR PRO; PR:Q54VY3; -.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0000124; C:SAGA complex; IEA:InterPro.
DR GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR InterPro; IPR021950; Spt20.
DR Pfam; PF12090; Spt20; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..1402
FT /note="Transcription factor SPT20 homolog"
FT /id="PRO_0000352462"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 60..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 114..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 177..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 786..817
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1136..1174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1199..1250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..29
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1227..1250
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1402 AA; 163174 MW; 0D57DCB10B73C5A5 CRC64;
MNGNSKVHTE ENKNEHQQEG KGGEQEQEQI NKHINKDTIN NNNNNNNSMS MEMDINSVSV
NSLSEPTPNE QQNNNNNNNS NGNGNGNDET TSSKTTTIIN SNPLDTDTIM HLNNNDSSNN
TTTTTIPRQS SSSIQNGIHK EENINQLTEI QLQPSLQIMD KEQQMNGIEE STTIATQTTL
PTNNNNNNNN NNNNNNNNNN NNNNILEKES NGVQEIEDSP NHLSLKRKLM ILEEMGLISD
DNNKNNNNNS IDIPNSNRLN QIPSSYKTSL YICLYPIGYA IDNIYKDKIF TYNDKISKDF
LNSISQGKLT PYIINILDQL SEQNDQKQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQTNNIYQ
NSNEITYYNG CIVVNIKDYR GFAENEQIAK TFNSKNMKPY PITVPIGTFK EFIEKRIILK
PTMESLLFDI KKNCSTLNND NKNNNINNIN NINNNNNNNN NNNNNNNNNI NINNNNNINN
YLNIKESEIV NEEYLLNFEK CLLHAITPQL ELSVNPNCFF DQLETKQKQL YNQSHSLFSY
KRFKPSDFIG LKYPVVYNNN NNNNNNNNKS YNNISNNNNN NVSNRFIKTH SISNIQERQQ
VNNNDLSTIS TQQSPPTLIQ TSAKRSIITL NTQINTTNSC LPNDNFSLFK FLNSNPKWVN
ERKSMLQYHS NINQTQSFPF NYQFNNNNNN NNNIPVNNNN NNVITQPPFG NGINTFSIKP
SIMTKIPIEC EQLNGRLLQF FSTSNLTVLT FECKAKPTGY ELLMYVSETT QVLNTLISLR
NLKFTAPSTS TSSSSSSGGT TTTTTATGTT PTTPTPVPLT QQQLIQQLIS FSLNKPILPL
NQQSPLAEAS YVLDTQLPQP TYLSFPIGNS KQAHFLINHM KSCIEHEGHY ILSYDSSFPD
TISSQAQEIR KKAEYIHNQQ QLNQQQQLQY HLQQQKQQQQ QQQQQQQQQN QQQQQQNQQQ
QQNQQNQQQN QQQNQQQNQQ QQQQQNQQNQ QNQQNQQQNQ QQQQQQNQQQ QQNQQTQQQQ
TQQQIQQNQQ QPTQQIQQQN QQQIQQNQQQ LQQQQLQQQQ QQIQQQQIQL QQQQIQQKQL
QQLQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQLQQ TRNLQPQQIQ
TQPLQQPPNQ MAQSMISPQS TPSTSPSPQQ QYQTTPVLQA GVQPQSQLTI KQPIQQPLQP
LQQPQPQPQQ QQQQQQQQPP QPQPQPQQFA QHLQQQQMQR PQAQLQPPQI LQQLQQQQQQ
QQQQLQPPQI LQQQYQTLQP QQLILQQQIH EKQNIHQQML LQQQRNQTNL QLLQQQAQQI
PPNNPQLLQT NQQQQQFVTQ QIQHQHQQLL QSQSIIQQLQ LQLHQQQQLQ QLQAQLQQQT
SPNIIQQQQQ QQQQQQQQQR IN