位置:首页 > 蛋白库 > SPT21_YEAST
SPT21_YEAST
ID   SPT21_YEAST             Reviewed;         758 AA.
AC   P35209; D6W002;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   03-AUG-2022, entry version 147.
DE   RecName: Full=Protein SPT21;
GN   Name=SPT21; OrderedLocusNames=YMR179W; ORFNames=YM8010.09;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8138180; DOI=10.1093/genetics/136.1.93;
RA   Natsoulis G., Winston F., Boeke J.D.;
RT   "The SPT10 and SPT21 genes of Saccharomyces cerevisiae.";
RL   Genetics 136:93-105(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169872;
RA   Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T.,
RA   Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K.,
RA   Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P.,
RA   Skelton J., Walsh S.V., Whitehead S., Barrell B.G.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.";
RL   Nature 387:90-93(1997).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [4]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-454, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=17287358; DOI=10.1073/pnas.0607084104;
RA   Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L.,
RA   Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.;
RT   "Analysis of phosphorylation sites on proteins from Saccharomyces
RT   cerevisiae by electron transfer dissociation (ETD) mass spectrometry.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007).
RN   [5]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=18407956; DOI=10.1074/mcp.m700468-mcp200;
RA   Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
RT   "A multidimensional chromatography technology for in-depth phosphoproteome
RT   analysis.";
RL   Mol. Cell. Proteomics 7:1389-1396(2008).
CC   -!- FUNCTION: Required for normal transcription at a number of loci in
CC       yeast.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L24436; AAA35078.1; -; Genomic_DNA.
DR   EMBL; Z49808; CAA89912.1; -; Genomic_DNA.
DR   EMBL; BK006946; DAA10076.1; -; Genomic_DNA.
DR   PIR; S47866; S47866.
DR   RefSeq; NP_013904.1; NM_001182685.1.
DR   AlphaFoldDB; P35209; -.
DR   BioGRID; 35357; 445.
DR   DIP; DIP-2855N; -.
DR   IntAct; P35209; 7.
DR   MINT; P35209; -.
DR   STRING; 4932.YMR179W; -.
DR   iPTMnet; P35209; -.
DR   PaxDb; P35209; -.
DR   PRIDE; P35209; -.
DR   EnsemblFungi; YMR179W_mRNA; YMR179W; YMR179W.
DR   GeneID; 855217; -.
DR   KEGG; sce:YMR179W; -.
DR   SGD; S000004791; SPT21.
DR   VEuPathDB; FungiDB:YMR179W; -.
DR   eggNOG; ENOG502QU3A; Eukaryota.
DR   HOGENOM; CLU_413915_0_0_1; -.
DR   InParanoid; P35209; -.
DR   OMA; QTNPMPA; -.
DR   BioCyc; YEAST:G3O-32867-MON; -.
DR   PRO; PR:P35209; -.
DR   Proteomes; UP000002311; Chromosome XIII.
DR   RNAct; P35209; protein.
DR   GO; GO:0000781; C:chromosome, telomeric region; IEA:GOC.
DR   GO; GO:0005634; C:nucleus; HDA:SGD.
DR   GO; GO:0000183; P:rDNA heterochromatin assembly; IMP:SGD.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IMP:SGD.
DR   GO; GO:0030466; P:silent mating-type cassette heterochromatin assembly; IGI:SGD.
DR   GO; GO:0031509; P:subtelomeric heterochromatin assembly; IMP:SGD.
DR   InterPro; IPR042403; Spt21/Ams2.
DR   PANTHER; PTHR39147; PTHR39147; 1.
PE   1: Evidence at protein level;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..758
FT                   /note="Protein SPT21"
FT                   /id="PRO_0000072162"
FT   REGION          251..271
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          372..414
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          438..471
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          624..651
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        394..414
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        627..651
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         454
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:17287358"
SQ   SEQUENCE   758 AA;  84697 MW;  7DB3FCF7EE996705 CRC64;
     MSELSQMTLK ILYTLDNGSN GSYLARSRAP KQVRVANIPS PFPTDSNEQT ELRIGAIHLK
     TILHEIYLNS PEVLDHDTLK DGYDYNLYYR DICEVDEPLV SLGLLSGLRK KFHKNSPYQY
     TENNIGEEES EERDEVTEEE YEDESFIVTG RVCSNVSALL RRSYSNISNK KGRVVNNQIP
     EETLEVKLRF TKVITNLRTS GNNTTNSRIS CLQMPSSLPS ATLPFTPKSQ SLFKTNQIKN
     SRNARTTITI NNTNSGTVGR RQTNPMPAPK AVRTQSLPIW NLKPNIANTG FPRNSIAHKI
     YLADRKTEAN QQNNQHQNIA YEINTLQNDN TIQRTKIDDS VSKRFDFMLN KRKSTKKVSP
     GIATIAKKPA SININPKQPP KTSGEKKAND KQTIVKVKNS NSKNSAKSTQ AGCRRSSVIE
     HLNDHDDSIL SDILSEPGIE GQKLQQKQKG RKISLTSEND KENIPPQSIT SKENKLEGDL
     DFNAEFPMSD FSDVVFKDEM GWFSNFNCNF FESPTSASAS QLNQQNLKPS ITLNDPNTCN
     TIALENEDVS ELETAQNNKI SLPSDVDKTS PIDSLSIPLI ELTHSSSTTN MQRISIKEGS
     TLNITDSNNA TPCDNDIKDR KASVIDSDNT KPQAGLINFS TPADQPASDN NVTASKKLTS
     MLETQQSKRS HEEVLDEEEE EEALKKQKAI PSSPCGMFNY HQPMELSEDI VEEEQGHNIG
     DDNESDKTND LFSTFIHSGI RVSQVVTSPI GEFQSIKH
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024