172L_IIV6
ID 172L_IIV6 Reviewed; 606 AA.
AC O55764; Q89442;
DT 16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 03-AUG-2022, entry version 83.
DE RecName: Full=Putative helicase 172L;
DE EC=3.6.4.-;
GN ORFNames=IIV6-172L;
OS Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC Pimascovirales; Iridoviridae; Betairidovirinae; Iridovirus.
OX NCBI_TaxID=176652;
OH NCBI_TaxID=6997; Acheta domesticus (House cricket).
OH NCBI_TaxID=168631; Chilo suppressalis (Asiatic rice borer moth).
OH NCBI_TaxID=6999; Gryllus bimaculatus (Two-spotted cricket).
OH NCBI_TaxID=58607; Gryllus campestris.
OH NCBI_TaxID=7108; Spodoptera frugiperda (Fall armyworm).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=11448171; DOI=10.1006/viro.2001.0963;
RA Jakob N.J., Mueller K., Bahr U., Darai G.;
RT "Analysis of the first complete DNA sequence of an invertebrate iridovirus:
RT coding strategy of the genome of Chilo iridescent virus.";
RL Virology 286:182-196(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=7698884; DOI=10.1159/000150390;
RA Sonntag K.-C., Schnitzler P., Janssen W., Darai G.;
RT "Identification of the primary structure and the coding capacity of the
RT genome of insect iridescent virus type 6 between the genome coordinates
RT 0.310 and 0.347 (7990 bp).";
RL Intervirology 37:287-297(1994).
RN [3]
RP GENOME REANNOTATION.
RX PubMed=17239238; DOI=10.1186/1743-422x-4-11;
RA Eaton H.E., Metcalf J., Penny E., Tcherepanov V., Upton C., Brunetti C.R.;
RT "Comparative genomic analysis of the family Iridoviridae: re-annotating and
RT defining the core set of iridovirus genes.";
RL Virol. J. 4:11-11(2007).
CC -!- SIMILARITY: Belongs to the SNF2/RAD54 helicase family. {ECO:0000305}.
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DR EMBL; AF303741; AAA62412.2; -; Genomic_DNA.
DR EMBL; S75674; AAB33905.1; -; Genomic_DNA.
DR PIR; T03177; T03177.
DR RefSeq; NP_149635.1; NC_003038.1.
DR SMR; O55764; -.
DR GeneID; 1732980; -.
DR KEGG; vg:1732980; -.
DR Proteomes; UP000001359; Genome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.10810; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR000330; SNF2_N.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; SSF52540; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding; Helicase; Hydrolase; Nucleotide-binding; Reference proteome.
FT CHAIN 1..606
FT /note="Putative helicase 172L"
FT /id="PRO_0000378036"
FT DOMAIN 59..264
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT DOMAIN 437..586
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00542"
FT BINDING 72..79
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT VARIANT 128..129
FT /note="RD -> KS"
FT VARIANT 446
FT /note="S -> M"
SQ SEQUENCE 606 AA; 69658 MW; CE96322F3801A6F5 CRC64;
MADAMNELCN LTQHLQVDDD QLSNLKLKNG YSLFPHQEKV MLWMKYRENL TKKECRKEGE
KTWGVRGGII SLCMGLGKTL TALAYSFQNK ASFPTLVITS KTVMHEWKTE GVEKFFDSDN
IRVLYLHRDY IKNIDKISRD DIMTYDIVIT TYDVCLFACK KGNYFLQCFE MGEEQSLMKN
KIVAIHTRKR KDANLPNLKG TAVIYGTPWE RVICDESQKF ANPKTMTYKC IMAVYGKYKW
CLTGTPIRNY ETDIWAQLRF CGYKGVERSH DWNRNGQGLI AFKDHNLISA IFTMSYDDAQ
MSLPEKTENN LTVKLEGQHK EIYEGILTET REMYKKMMND LCSFTYVLAM FTRLRQCAIA
PYLITPDAKR NSKEKKNCSE WCLDKFGGAG IKSSKILKIV EIIKSVTLND NPNCNSNPKS
LQLLAKEKAY SCFGSDYIKS SNFEISHPTK IIVFSMFTSC LDLLSEAIKE DYPNFKFVQV
DGDTKNRSEL FDQFKNDINT QGLFLTYKVG SEGLNLTEAT HCICIEPWWT NAVHNQAKAR
LWRTGQTKQV YVHNVIIEGS IEEKIVEICK GKDDMAASYL EGKERIKSPV RAPKLDKFTL
GKMLGI