ID   SPVA_SALDU              Reviewed;         255 AA.
AC   P24418;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Virulence protein SpvA;
DE   AltName: Full=28.1 kDa virulence protein;
GN   Name=spvA; Synonyms=vsdB;
OS   Salmonella dublin.
OG   Plasmid pSDL2.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=98360;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Lane;
RX   PubMed=2041471; DOI=10.1111/j.1365-2958.1991.tb02111.x;
RA   Krause M., Roudier C., Fierer J., Harwood J., Guiney D.;
RT   "Molecular analysis of the virulence locus of the Salmonella dublin plasmid
RT   pSDL2.";
RL   Mol. Microbiol. 5:307-316(1991).
RN   [2]
RP   DISRUPTION PHENOTYPE UPON MOUSE INFECTION.
RC   STRAIN=Lane;
RX   PubMed=1400193; DOI=10.1128/jb.174.20.6418-6423.1992;
RA   Roudier C., Fierer J., Guiney D.G.;
RT   "Characterization of translation termination mutations in the spv operon of
RT   the Salmonella virulence plasmid pSDL2.";
RL   J. Bacteriol. 174:6418-6423(1992).
CC   -!- FUNCTION: Part of a Salmonella virulence gene cluster.
CC   -!- DISRUPTION PHENOTYPE: No effect on virulence in mice.
CC       {ECO:0000269|PubMed:1400193}.
CC   -!- MISCELLANEOUS: In Salmonella spp. the spv gene cluster is encoded on a
CC       highly transmissible plasmid.
CC   -!- SIMILARITY: Belongs to the SpvA family. {ECO:0000305}.
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DR   EMBL; X56727; CAA40048.1; -; Genomic_DNA.
DR   RefSeq; WP_001575487.1; NZ_VDCP01000013.1.
DR   RefSeq; YP_001716112.1; NC_010422.1.
DR   RefSeq; YP_006954903.1; NC_019106.1.
DR   AlphaFoldDB; P24418; -.
DR   PRIDE; P24418; -.
DR   OMA; RCLFREN; -.
DR   InterPro; IPR018003; Insecticidal_toxin/plasmid_vir.
DR   InterPro; IPR003518; Sal_SpvA.
DR   Pfam; PF03538; VRP1; 2.
DR   PRINTS; PR01340; SALSPVAPROT.
PE   3: Inferred from homology;
KW   Plasmid; Virulence.
FT   CHAIN           1..255
FT                   /note="Virulence protein SpvA"
FT                   /id="PRO_0000221660"
SQ   SEQUENCE   255 AA;  28156 MW;  A3DF4AA6E204F80F CRC64;
     MNMNQTTSPA LSQVETAIRA PAGNFAKYNY YSVFDIVRQT RKQFINANMS WPGSRGGKAW
     DLAMGQAQYI RCMFRENQLT RRVRGTLQQT PDNGTNLSSS AVGGIQGQAE RRPDLATLMV
     VNDAINQQIP TLLPYHFPHD QVELSLLNTD VSLEDIISES SIDWPWFLSN SLTGDNSNYA
     MELASRLSPE QQTLPTEPDN STATDLTSFY QTNLGLKTAD YTPFEALNTF ARQLAITVPP
     GGTVDCGYSA CQPAV