ID   SPXH_ALKCK              Reviewed;         300 AA.
AC   Q5WF00;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=ClpXP adapter protein SpxH {ECO:0000255|HAMAP-Rule:MF_02245};
GN   Name=spxH {ECO:0000255|HAMAP-Rule:MF_02245}; OrderedLocusNames=ABC2525;
OS   Alkalihalobacillus clausii (strain KSM-K16) (Bacillus clausii).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalobacillus.
OX   NCBI_TaxID=66692;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KSM-K16;
RA   Takaki Y., Kageyama Y., Shimamura S., Suzuki H., Nishi S., Hatada Y.,
RA   Kawai S., Ito S., Horikoshi K.;
RT   "The complete genome sequence of the alkaliphilic Bacillus clausii KSM-
RT   K16.";
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Adapter protein required for efficient degradation of Spx by
CC       ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx
CC       and exposes the C-terminus of Spx for recognition and proteolysis by
CC       ClpXP. {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SUBUNIT: Interacts with Spx. {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SIMILARITY: Belongs to the SpxH family. {ECO:0000255|HAMAP-
CC       Rule:MF_02245}.
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DR   EMBL; AP006627; BAD65060.1; -; Genomic_DNA.
DR   RefSeq; WP_011247368.1; NC_006582.1.
DR   AlphaFoldDB; Q5WF00; -.
DR   SMR; Q5WF00; -.
DR   STRING; 66692.ABC2525; -.
DR   EnsemblBacteria; BAD65060; BAD65060; ABC2525.
DR   KEGG; bcl:ABC2525; -.
DR   eggNOG; COG2761; Bacteria.
DR   HOGENOM; CLU_069785_0_0_9; -.
DR   OMA; YRMGGLL; -.
DR   OrthoDB; 996965at2; -.
DR   Proteomes; UP000001168; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_02245; Adapter_SpxH; 1.
DR   InterPro; IPR046404; Adapter_SpxH.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   SUPFAM; SSF52833; SSF52833; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..300
FT                   /note="ClpXP adapter protein SpxH"
FT                   /id="PRO_0000278681"
SQ   SEQUENCE   300 AA;  33452 MW;  0680F9272639CD48 CRC64;
     MNAKHRVTSH CDHELGICGI SPEANEALPA KKPLEIYTFI DPLCAQCWSM EPILKKLKVE
     YGHYFRIRVL LAGKLNVWNA CEAGKAKYTR PPVWVKGVSS SNMPYAGDIK LSDFHPYKAS
     LAIKAAELQG PKAGHRFLRK LRETLFLQKQ NITNEDVLKA CANAAGLDVD AFIADLHSPS
     AAKALQCDVQ TTNEMDVDTV PTFVFFNDNS EEAGIKISGQ YPFSIYVQLL EDMLGFVPVK
     ATPPTLEGLL QTYGFLATAE VAMVLDLSSE EAEKKLKTLM LQQKVEAVPY EYGTFWKWLM