ID   SPXH_ALKHC              Reviewed;         306 AA.
AC   Q9K8Z7;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=ClpXP adapter protein SpxH {ECO:0000255|HAMAP-Rule:MF_02245};
GN   Name=spxH {ECO:0000255|HAMAP-Rule:MF_02245}; OrderedLocusNames=BH2855;
OS   Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344
OS   / JCM 9153 / C-125) (Bacillus halodurans).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalobacillus.
OX   NCBI_TaxID=272558;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125;
RX   PubMed=11058132; DOI=10.1093/nar/28.21.4317;
RA   Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F.,
RA   Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.;
RT   "Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans
RT   and genomic sequence comparison with Bacillus subtilis.";
RL   Nucleic Acids Res. 28:4317-4331(2000).
CC   -!- FUNCTION: Adapter protein required for efficient degradation of Spx by
CC       ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx
CC       and exposes the C-terminus of Spx for recognition and proteolysis by
CC       ClpXP. {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SUBUNIT: Interacts with Spx. {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SIMILARITY: Belongs to the SpxH family. {ECO:0000255|HAMAP-
CC       Rule:MF_02245}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000004; BAB06574.1; -; Genomic_DNA.
DR   PIR; G84006; G84006.
DR   RefSeq; WP_010899002.1; NC_002570.2.
DR   AlphaFoldDB; Q9K8Z7; -.
DR   SMR; Q9K8Z7; -.
DR   STRING; 272558.10175476; -.
DR   EnsemblBacteria; BAB06574; BAB06574; BAB06574.
DR   KEGG; bha:BH2855; -.
DR   eggNOG; COG2761; Bacteria.
DR   HOGENOM; CLU_069785_0_0_9; -.
DR   OMA; YRMGGLL; -.
DR   OrthoDB; 996965at2; -.
DR   Proteomes; UP000001258; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_02245; Adapter_SpxH; 1.
DR   InterPro; IPR046404; Adapter_SpxH.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   SUPFAM; SSF52833; SSF52833; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..306
FT                   /note="ClpXP adapter protein SpxH"
FT                   /id="PRO_0000278678"
SQ   SEQUENCE   306 AA;  35574 MW;  42369448E7774AA1 CRC64;
     MAHHENQTNC NDERGICSLD SDADDQKQKK RKPLEIYTFI DPLCPECWAF EPILKKLQVE
     YGQYFRIRFI VAGKLEAWNL CRGKYKGAQS REDLAHVWRK ITETFGMPCD GDVWLEDPIT
     SSYTPSLAIK AAELQGPQAG VRFLRKLREH LFLNKQNVTK EDILISCAQR AGLDVKEFKQ
     DLHSKGAAKA LRCDMQTTKE MDVDLVPTFV FFNDNVDEEG IKVTGHYPYH IYVQILEDML
     GFKPERQPPM SLEHFLKKYE FVASIEVAVV FDLEIDEAEK QLKKLVLKQK LELVPMKYGN
     FWRYLE