ID   SPXH_BACAN              Reviewed;         297 AA.
AC   Q81TQ8; Q6I1Z3; Q6KVT2;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=ClpXP adapter protein SpxH {ECO:0000255|HAMAP-Rule:MF_02245};
GN   Name=spxH {ECO:0000255|HAMAP-Rule:MF_02245};
GN   OrderedLocusNames=BA_1208, GBAA_1208, BAS1115;
OS   Bacillus anthracis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=1392;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ames / isolate Porton;
RX   PubMed=12721629; DOI=10.1038/nature01586;
RA   Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T.,
RA   Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R.,
RA   Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M.,
RA   Kolonay J.F., Beanan M.J., Dodson R.J., Brinkac L.M., Gwinn M.L.,
RA   DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C.,
RA   Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y.,
RA   Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M.,
RA   Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E.,
RA   White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M.,
RA   Hanna P.C., Kolstoe A.-B., Fraser C.M.;
RT   "The genome sequence of Bacillus anthracis Ames and comparison to closely
RT   related bacteria.";
RL   Nature 423:81-86(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ames ancestor;
RX   PubMed=18952800; DOI=10.1128/jb.01347-08;
RA   Ravel J., Jiang L., Stanley S.T., Wilson M.R., Decker R.S., Read T.D.,
RA   Worsham P., Keim P.S., Salzberg S.L., Fraser-Liggett C.M., Rasko D.A.;
RT   "The complete genome sequence of Bacillus anthracis Ames 'Ancestor'.";
RL   J. Bacteriol. 191:445-446(2009).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sterne;
RA   Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K.,
RA   Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R.,
RA   Richardson P., Rubin E., Tice H.;
RT   "Complete genome sequence of Bacillus anthracis Sterne.";
RL   Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Adapter protein required for efficient degradation of Spx by
CC       ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx
CC       and exposes the C-terminus of Spx for recognition and proteolysis by
CC       ClpXP. {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SUBUNIT: Interacts with Spx. {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SIMILARITY: Belongs to the SpxH family. {ECO:0000255|HAMAP-
CC       Rule:MF_02245}.
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DR   EMBL; AE016879; AAP25169.1; -; Genomic_DNA.
DR   EMBL; AE017334; AAT30294.1; -; Genomic_DNA.
DR   EMBL; AE017225; AAT53438.1; -; Genomic_DNA.
DR   RefSeq; NP_843683.1; NC_003997.3.
DR   RefSeq; WP_000360662.1; NZ_WXXJ01000044.1.
DR   RefSeq; YP_027387.1; NC_005945.1.
DR   AlphaFoldDB; Q81TQ8; -.
DR   SMR; Q81TQ8; -.
DR   STRING; 261594.GBAA_1208; -.
DR   DNASU; 1086926; -.
DR   EnsemblBacteria; AAP25169; AAP25169; BA_1208.
DR   EnsemblBacteria; AAT30294; AAT30294; GBAA_1208.
DR   GeneID; 45021212; -.
DR   KEGG; ban:BA_1208; -.
DR   KEGG; bar:GBAA_1208; -.
DR   KEGG; bat:BAS1115; -.
DR   PATRIC; fig|198094.11.peg.1184; -.
DR   eggNOG; COG2761; Bacteria.
DR   HOGENOM; CLU_069785_0_0_9; -.
DR   OMA; YRMGGLL; -.
DR   Proteomes; UP000000427; Chromosome.
DR   Proteomes; UP000000594; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_02245; Adapter_SpxH; 1.
DR   InterPro; IPR046404; Adapter_SpxH.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   SUPFAM; SSF52833; SSF52833; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..297
FT                   /note="ClpXP adapter protein SpxH"
FT                   /id="PRO_0000278674"
SQ   SEQUENCE   297 AA;  34386 MW;  0660963E3F000CB6 CRC64;
     MDKQEAKHIN MPSPSACEYK SVEAYLFIDP LCKDCWEIEP FIIKLWLEYG KYFSIRHIVT
     GKVDGTNASS HKWNKPANIR FVWEKTTSLH GFSYDGKVHM QEASSTPYLV SMAIKAAELQ
     GRKAGSKFLR KLQEYIFLEN VSNPDCELLL ACAKDSDIDV EEFKKDLYSA SAKKAFQCDL
     KFTNEMHITE IPSLVFFHAN SDEEGIKIAG TYSYDVYVQL LKELVKCEIE PEPLPSLEVL
     LEATQFISSK EVAFIYDCSK QEIERELKKL QLKRKVQMID VKCERYWKWI AKEKDLV