ID   SPXH_BACC1              Reviewed;         297 AA.
AC   Q73BV2;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=ClpXP adapter protein SpxH {ECO:0000255|HAMAP-Rule:MF_02245};
GN   Name=spxH {ECO:0000255|HAMAP-Rule:MF_02245}; OrderedLocusNames=BCE_1316;
OS   Bacillus cereus (strain ATCC 10987 / NRS 248).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=222523;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10987 / NRS 248;
RX   PubMed=14960714; DOI=10.1093/nar/gkh258;
RA   Rasko D.A., Ravel J., Oekstad O.A., Helgason E., Cer R.Z., Jiang L.,
RA   Shores K.A., Fouts D.E., Tourasse N.J., Angiuoli S.V., Kolonay J.F.,
RA   Nelson W.C., Kolstoe A.-B., Fraser C.M., Read T.D.;
RT   "The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic
RT   adaptations and a large plasmid related to Bacillus anthracis pXO1.";
RL   Nucleic Acids Res. 32:977-988(2004).
CC   -!- FUNCTION: Adapter protein required for efficient degradation of Spx by
CC       ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx
CC       and exposes the C-terminus of Spx for recognition and proteolysis by
CC       ClpXP. {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SUBUNIT: Interacts with Spx. {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SIMILARITY: Belongs to the SpxH family. {ECO:0000255|HAMAP-
CC       Rule:MF_02245}.
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DR   EMBL; AE017194; AAS40245.1; -; Genomic_DNA.
DR   RefSeq; WP_000360652.1; NC_003909.8.
DR   AlphaFoldDB; Q73BV2; -.
DR   SMR; Q73BV2; -.
DR   EnsemblBacteria; AAS40245; AAS40245; BCE_1316.
DR   GeneID; 59159017; -.
DR   KEGG; bca:BCE_1316; -.
DR   HOGENOM; CLU_069785_0_0_9; -.
DR   OMA; YRMGGLL; -.
DR   Proteomes; UP000002527; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_02245; Adapter_SpxH; 1.
DR   InterPro; IPR046404; Adapter_SpxH.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   SUPFAM; SSF52833; SSF52833; 1.
PE   3: Inferred from homology;
KW   Cytoplasm.
FT   CHAIN           1..297
FT                   /note="ClpXP adapter protein SpxH"
FT                   /id="PRO_0000278675"
SQ   SEQUENCE   297 AA;  34300 MW;  9D33FE6C032CBA6E CRC64;
     MDKQEAKHIN MPSPSACEHK SVEAYLFIDP LCKDCWEIEP FIIKLWLEYG KYFSIRHIVT
     GKVDGTNASS HKWNKPANIR FVWEKTTSLQ GFSCDGKVHM QEASSTPYLV SMAIKAAELQ
     GRKAGSKFLR KLQEYIFLEN VSNPDCELLL ACAKDSNIDV EEFKKDLYSA SAKKAFQCDL
     KFTNEMHITE IPSLVFFHAN SDEEGIKIAG TYSYDVYVQL LKELVKCEIE PEPLPPLEVL
     LEATQFISSK EVAFIYDCSK QEIERELKKL QLKRKVQMID VKCERYWKWI AKEKDLV