ID   SPXH_BACCR              Reviewed;         297 AA.
AC   Q813V3;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=ClpXP adapter protein SpxH {ECO:0000255|HAMAP-Rule:MF_02245};
GN   Name=spxH {ECO:0000255|HAMAP-Rule:MF_02245}; OrderedLocusNames=BC_1194;
OS   Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC
OS   15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=226900;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373
RC   / NCTC 2599 / NRRL B-3711;
RX   PubMed=12721630; DOI=10.1038/nature01582;
RA   Ivanova N., Sorokin A., Anderson I., Galleron N., Candelon B., Kapatral V.,
RA   Bhattacharyya A., Reznik G., Mikhailova N., Lapidus A., Chu L., Mazur M.,
RA   Goltsman E., Larsen N., D'Souza M., Walunas T., Grechkin Y., Pusch G.,
RA   Haselkorn R., Fonstein M., Ehrlich S.D., Overbeek R., Kyrpides N.C.;
RT   "Genome sequence of Bacillus cereus and comparative analysis with Bacillus
RT   anthracis.";
RL   Nature 423:87-91(2003).
CC   -!- FUNCTION: Adapter protein required for efficient degradation of Spx by
CC       ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx
CC       and exposes the C-terminus of Spx for recognition and proteolysis by
CC       ClpXP. {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SUBUNIT: Interacts with Spx. {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SIMILARITY: Belongs to the SpxH family. {ECO:0000255|HAMAP-
CC       Rule:MF_02245}.
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DR   EMBL; AE016877; AAP08180.1; -; Genomic_DNA.
DR   RefSeq; NP_830979.1; NC_004722.1.
DR   RefSeq; WP_000360645.1; NZ_CP034551.1.
DR   AlphaFoldDB; Q813V3; -.
DR   SMR; Q813V3; -.
DR   STRING; 226900.BC_1194; -.
DR   EnsemblBacteria; AAP08180; AAP08180; BC_1194.
DR   GeneID; 67505913; -.
DR   KEGG; bce:BC1194; -.
DR   PATRIC; fig|226900.8.peg.1162; -.
DR   HOGENOM; CLU_069785_0_0_9; -.
DR   OMA; YRMGGLL; -.
DR   Proteomes; UP000001417; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_02245; Adapter_SpxH; 1.
DR   InterPro; IPR046404; Adapter_SpxH.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   SUPFAM; SSF52833; SSF52833; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..297
FT                   /note="ClpXP adapter protein SpxH"
FT                   /id="PRO_0000278676"
SQ   SEQUENCE   297 AA;  34311 MW;  2EA33A1D09381708 CRC64;
     MDKQEAKHIN MPSPSACEHK SVEAYLFIDP LCKDCWEIEP FIIKLWLEYG KYFSIRHIVT
     GKVDGTNASS HKWNKPANIR FVWEKTTSLQ GFSCDGKVHM QEASSTPYLV SMAIKAAELQ
     GRKAGSKFLR KLQEYIFLEN VSNPDCELLL ACAKDSNIDV EEFKKDLHSA SAKKAFQCDL
     KFTNEMHITE IPSLVFFHAN SDEEGIKIAG NYSYDVYVQL LKELVKCEIE PEPLPPLEVL
     LEATQFISSK EVAFIYDCPQ QEIERELKKL QLKRKVQMIE VKCERYWKWI AKEKDLV