ID   SPXH_LISIN              Reviewed;         272 AA.
AC   Q92D57;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=ClpXP adapter protein SpxH {ECO:0000255|HAMAP-Rule:MF_02245};
GN   Name=spxH {ECO:0000255|HAMAP-Rule:MF_02245}; OrderedLocusNames=lin0963;
OS   Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=272626;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-680 / CLIP 11262;
RX   PubMed=11679669; DOI=10.1126/science.1063447;
RA   Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F.,
RA   Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A.,
RA   Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E.,
RA   Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O., Entian K.-D.,
RA   Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W.,
RA   Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U.,
RA   Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A.,
RA   Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B.,
RA   Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N.,
RA   Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P.;
RT   "Comparative genomics of Listeria species.";
RL   Science 294:849-852(2001).
CC   -!- FUNCTION: Adapter protein required for efficient degradation of Spx by
CC       ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx
CC       and exposes the C-terminus of Spx for recognition and proteolysis by
CC       ClpXP. {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SUBUNIT: Interacts with Spx. {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SIMILARITY: Belongs to the SpxH family. {ECO:0000255|HAMAP-
CC       Rule:MF_02245}.
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DR   EMBL; AL596167; CAC96194.1; -; Genomic_DNA.
DR   PIR; AB1553; AB1553.
DR   RefSeq; WP_010990696.1; NC_003212.1.
DR   AlphaFoldDB; Q92D57; -.
DR   SMR; Q92D57; -.
DR   STRING; 272626.lin0963; -.
DR   DNASU; 1129473; -.
DR   EnsemblBacteria; CAC96194; CAC96194; CAC96194.
DR   KEGG; lin:lin0963; -.
DR   eggNOG; COG2761; Bacteria.
DR   HOGENOM; CLU_069785_0_0_9; -.
DR   OMA; YRMGGLL; -.
DR   OrthoDB; 996965at2; -.
DR   Proteomes; UP000002513; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_02245; Adapter_SpxH; 1.
DR   InterPro; IPR046404; Adapter_SpxH.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   SUPFAM; SSF52833; SSF52833; 1.
PE   3: Inferred from homology;
KW   Cytoplasm.
FT   CHAIN           1..272
FT                   /note="ClpXP adapter protein SpxH"
FT                   /id="PRO_0000278684"
SQ   SEQUENCE   272 AA;  31373 MW;  5A737E99519C3ECC CRC64;
     MINQNLYYQS VANSKPIEIY LFFDPACDDC WNIEANMLRL QMEYGNYFKL RYVLHNNLQT
     FVCKQKRAGN SNLSLKEQQI GAHLSYISCL AVKAAELQGK KQGITFLRKI QEAYFLENKD
     IASEEVLYEI AISTGLDLTE FKKDLASTAA KRAYIGDQKV AQEMEIRENP TVVFFNKNIE
     DAGLKLSGLH RYEVYVHVLS ELLNDFPEPE ERPQMEEYLA KVKVTSSASM AAFYGVSEQQ
     IDRQMKKWRL QQKVELIDAP DGKPHWKYIG SL