ID   SPXH_LISMO              Reviewed;         272 AA.
AC   Q8Y8E0;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=ClpXP adapter protein SpxH {ECO:0000255|HAMAP-Rule:MF_02245};
GN   Name=spxH {ECO:0000255|HAMAP-Rule:MF_02245}; OrderedLocusNames=lmo0964;
OS   Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=169963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-679 / EGD-e;
RX   PubMed=11679669; DOI=10.1126/science.1063447;
RA   Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F.,
RA   Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A.,
RA   Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E.,
RA   Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O., Entian K.-D.,
RA   Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W.,
RA   Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U.,
RA   Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A.,
RA   Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B.,
RA   Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N.,
RA   Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P.;
RT   "Comparative genomics of Listeria species.";
RL   Science 294:849-852(2001).
CC   -!- FUNCTION: Adapter protein required for efficient degradation of Spx by
CC       ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx
CC       and exposes the C-terminus of Spx for recognition and proteolysis by
CC       ClpXP. {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SUBUNIT: Interacts with Spx. {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SIMILARITY: Belongs to the SpxH family. {ECO:0000255|HAMAP-
CC       Rule:MF_02245}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL591977; CAC99042.1; -; Genomic_DNA.
DR   PIR; AD1195; AD1195.
DR   RefSeq; NP_464489.1; NC_003210.1.
DR   RefSeq; WP_003722785.1; NZ_CP023861.1.
DR   AlphaFoldDB; Q8Y8E0; -.
DR   SMR; Q8Y8E0; -.
DR   STRING; 169963.lmo0964; -.
DR   PaxDb; Q8Y8E0; -.
DR   EnsemblBacteria; CAC99042; CAC99042; CAC99042.
DR   GeneID; 986468; -.
DR   KEGG; lmo:lmo0964; -.
DR   PATRIC; fig|169963.11.peg.991; -.
DR   eggNOG; COG2761; Bacteria.
DR   HOGENOM; CLU_069785_0_0_9; -.
DR   OMA; YRMGGLL; -.
DR   PhylomeDB; Q8Y8E0; -.
DR   BioCyc; LMON169963:LMO0964-MON; -.
DR   Proteomes; UP000000817; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_02245; Adapter_SpxH; 1.
DR   InterPro; IPR046404; Adapter_SpxH.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   SUPFAM; SSF52833; SSF52833; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..272
FT                   /note="ClpXP adapter protein SpxH"
FT                   /id="PRO_0000278686"
SQ   SEQUENCE   272 AA;  31222 MW;  30776C209F7B5A4D CRC64;
     MINQNLYYQS VANSKPIEIY LFFDPACDDC WNIEANMLRL QMEYGNYFKL RYVLHNNLQT
     FVCKQKRAGN SNLSLKEQQI GAHLSYISCL AVKAAELQGK KQGITFLRKI QAAYFLENKD
     IASDEVLYDI AVSTGLDLSE FKKDLASTVA KRAYIGDQKV AQEMEIHENP TVVFFNKNIE
     DAGLKLSGLH RYEVYVHVLS ELLNDAPQPE ERPQMEEYLA KVKVTSSASM ADFYGVSEQQ
     IERQMKKWRL QQKVELIDAP AGQSHWKYIG NL