ID   SPXH_OCEIH              Reviewed;         307 AA.
AC   Q8ERT3;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=ClpXP adapter protein SpxH {ECO:0000255|HAMAP-Rule:MF_02245};
GN   Name=spxH {ECO:0000255|HAMAP-Rule:MF_02245}; OrderedLocusNames=OB1217;
OS   Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC
OS   3954 / HTE831).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Oceanobacillus.
OX   NCBI_TaxID=221109;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831;
RX   PubMed=12235376; DOI=10.1093/nar/gkf526;
RA   Takami H., Takaki Y., Uchiyama I.;
RT   "Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge
RT   and its unexpected adaptive capabilities to extreme environments.";
RL   Nucleic Acids Res. 30:3927-3935(2002).
CC   -!- FUNCTION: Adapter protein required for efficient degradation of Spx by
CC       ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx
CC       and exposes the C-terminus of Spx for recognition and proteolysis by
CC       ClpXP. {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SUBUNIT: Interacts with Spx. {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SIMILARITY: Belongs to the SpxH family. {ECO:0000255|HAMAP-
CC       Rule:MF_02245}.
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DR   EMBL; BA000028; BAC13173.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8ERT3; -.
DR   SMR; Q8ERT3; -.
DR   STRING; 221109.22776899; -.
DR   EnsemblBacteria; BAC13173; BAC13173; BAC13173.
DR   KEGG; oih:OB1217; -.
DR   eggNOG; COG2761; Bacteria.
DR   HOGENOM; CLU_069785_0_0_9; -.
DR   OMA; YRMGGLL; -.
DR   OrthoDB; 996965at2; -.
DR   PhylomeDB; Q8ERT3; -.
DR   Proteomes; UP000000822; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_02245; Adapter_SpxH; 1.
DR   InterPro; IPR046404; Adapter_SpxH.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   SUPFAM; SSF52833; SSF52833; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..307
FT                   /note="ClpXP adapter protein SpxH"
FT                   /id="PRO_0000278687"
SQ   SEQUENCE   307 AA;  35812 MW;  70CBAC2771A4522C CRC64;
     MSWNQQELTS SNHTNTSPNF NYINYVQKPI EMYVFIDPLC AECWSLEPYI KKLSVEYGRF
     FTIRQIVSGQ LSNLNVDVFE KPKKLKDIWE RTAKRTGMSC DGDIWDENPI DYPYVPSLAI
     KAAELQGKKA GKMFVRKLQE NLFINKENIS EEKILLNCAT EANLDLEEFE RDLFSSSAKK
     ALQCDLKLTR EMEVDYIPTI VFFNQSVEEE GVKISGLYPY EIYKLVLKEI LQKTPIPSST
     PPLIDFLKHY QVVGTKEISV VYDWSLDKTE KEMKKLQFQQ IVERIPAKYG SFWKYIDRSK
     TQDAAQR