ID   SPXH_STAHJ              Reviewed;         265 AA.
AC   Q4L510;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=ClpXP adapter protein SpxH {ECO:0000255|HAMAP-Rule:MF_02245};
GN   Name=spxH {ECO:0000255|HAMAP-Rule:MF_02245}; OrderedLocusNames=SH1956;
OS   Staphylococcus haemolyticus (strain JCSC1435).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=279808;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCSC1435;
RX   PubMed=16237012; DOI=10.1128/jb.187.21.7292-7308.2005;
RA   Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y.,
RA   Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C.,
RA   Hiramatsu K.;
RT   "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the
RT   extreme plasticity of its genome and the evolution of human-colonizing
RT   staphylococcal species.";
RL   J. Bacteriol. 187:7292-7308(2005).
CC   -!- FUNCTION: Adapter protein required for efficient degradation of Spx by
CC       ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx
CC       and exposes the C-terminus of Spx for recognition and proteolysis by
CC       ClpXP. {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SUBUNIT: Interacts with Spx. {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02245}.
CC   -!- SIMILARITY: Belongs to the SpxH family. {ECO:0000255|HAMAP-
CC       Rule:MF_02245}.
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DR   EMBL; AP006716; BAE05265.1; -; Genomic_DNA.
DR   RefSeq; WP_011276226.1; NC_007168.1.
DR   AlphaFoldDB; Q4L510; -.
DR   SMR; Q4L510; -.
DR   STRING; 279808.SH1956; -.
DR   PRIDE; Q4L510; -.
DR   EnsemblBacteria; BAE05265; BAE05265; SH1956.
DR   GeneID; 58061931; -.
DR   KEGG; sha:SH1956; -.
DR   eggNOG; COG2761; Bacteria.
DR   HOGENOM; CLU_069785_0_0_9; -.
DR   OMA; YRMGGLL; -.
DR   OrthoDB; 996965at2; -.
DR   Proteomes; UP000000543; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_02245; Adapter_SpxH; 1.
DR   InterPro; IPR046404; Adapter_SpxH.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   SUPFAM; SSF52833; SSF52833; 1.
PE   3: Inferred from homology;
KW   Cytoplasm.
FT   CHAIN           1..265
FT                   /note="ClpXP adapter protein SpxH"
FT                   /id="PRO_0000278700"
SQ   SEQUENCE   265 AA;  31177 MW;  2C063ADBFF3C4FC8 CRC64;
     MAEELKIVDN RSREDANLSP VNKIEIYSFF DPFNTDCFKL SAIISKLRIE YNQYIRIRHI
     LNPSLKVLTK CQAQSTSDFD NIALAYKAAE LQGRLRAERF IHLMQNEIIP KKDIITEEMI
     CDCIINAGLD YNEFKEDLQK SKLTESLKID LHIAREMEIE QAPSLVFFSE DVHEEGLKVE
     GLYPYHIYTY IINELMGTPI EKNLPPKIEH YIQKKQLVTT EELLTIYEWP EKLMTKELKK
     LALQQKVEKL QYPEGDFWQS KMPRI