ID   SPXM1_ORYSI             Reviewed;         697 AA.
AC   A2X8A7;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2010, sequence version 2.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=SPX domain-containing membrane protein OsI_08463;
GN   ORFNames=OsI_08463;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAY87067.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; CM000127; EAY87067.1; ALT_SEQ; Genomic_DNA.
DR   AlphaFoldDB; A2X8A7; -.
DR   STRING; 39946.A2X8A7; -.
DR   Proteomes; UP000007015; Chromosome 2.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd14479; SPX-MFS_plant; 1.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR004331; SPX_dom.
DR   InterPro; IPR045264; SPXM_SPX_plant.
DR   Pfam; PF07690; MFS_1; 1.
DR   Pfam; PF03105; SPX; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS51382; SPX; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..697
FT                   /note="SPX domain-containing membrane protein OsI_08463"
FT                   /id="PRO_0000398570"
FT   TRANSMEM        247..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        278..298
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        315..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        338..356
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        375..395
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        411..431
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        513..533
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        544..564
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        576..596
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        604..624
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        670..690
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          2..145
FT                   /note="SPX"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00714"
SQ   SEQUENCE   697 AA;  77951 MW;  CB5EE7426074B6D3 CRC64;
     MVNFGKRLMA DQLEEWKEYY INYKMMKKKV KQYVQQTQNG GRNREQVLKE FSRMLDDQIE
     KIVLFLLQQQ GHLASRIEKL GEERALLMEQ ADASQISELR EAYREVGIDL MKLLRFVDMN
     ATGIRKILKK FDKRFGYKFT DYYVSTRANH PCSQLQQIFK QVGIVAVVGA LSRNLAFLQD
     HQGNFPSIYD HPSITLKDPI IEQINHSVQK LTHATNLLQF IGQHALIIPE DMHSGSEDLV
     DDQSYHFMSL LLNLANTFLY MVNTYIIVPT ADDYSVSLGA AATVCGVIIG SMAVAQVFSS
     VYFSAWSNKS YFRPLVFSSI MLFLGNLLYA LAYDVNSLTV LIVGRLLCGL GSARAVNRRY
     ISDCVPLKTR LQASAGFVSA SALGMACGPA LAGLLQTNFK IYGFTFDQNT LPGWIMCLAW
     ITYLFWLWIS FKEPDHIVRE NSVNTPSSDS GHRRNSNLED GLAQPFLIDA KESLDENGED
     NDENEEDPED SHKPATSLAA AYRLLTPSVK VQLLIYFMLK FAMEILLSES SVVTTFYFNW
     STSTVAMFLA VLGLTVLPVN VIVGSYVTNL FQDRQILVAS EIMVLIGIAM SFRFTSHYSV
     PQYVSSALIT FVFAEVLEGV NLSLLSRVMS SRLSRGTYNG GLLSTEAGTL ARVAADMTIT
     AAGYLGQNSL LNVTLLPSFV ICVASIVATF CTYNSLY