ID   SPXM3_ORYSI             Reviewed;         698 AA.
AC   A2Y8U6;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=SPX domain-containing membrane protein OsI_21475;
GN   ORFNames=OsI_21475;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000305}.
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DR   EMBL; CM000131; EAY99506.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2Y8U6; -.
DR   STRING; 39946.A2Y8U6; -.
DR   iPTMnet; A2Y8U6; -.
DR   EnsemblPlants; BGIOSGA022231-TA; BGIOSGA022231-PA; BGIOSGA022231.
DR   Gramene; BGIOSGA022231-TA; BGIOSGA022231-PA; BGIOSGA022231.
DR   HOGENOM; CLU_025236_1_0_1; -.
DR   OMA; MTNYYIV; -.
DR   Proteomes; UP000007015; Chromosome 6.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd14479; SPX-MFS_plant; 1.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR004331; SPX_dom.
DR   InterPro; IPR045264; SPXM_SPX_plant.
DR   Pfam; PF07690; MFS_1; 1.
DR   Pfam; PF03105; SPX; 2.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS51382; SPX; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..698
FT                   /note="SPX domain-containing membrane protein OsI_21475"
FT                   /id="PRO_0000398574"
FT   TRANSMEM        248..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        279..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        316..336
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        339..357
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        376..396
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        412..432
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        514..534
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        545..565
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        577..597
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        605..625
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        671..691
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          2..145
FT                   /note="SPX"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00714"
FT   REGION          467..495
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   698 AA;  77650 MW;  FF082AB186330B32 CRC64;
     MVNFGKKLMA DQIPEWKGYY INYKLMKKKV KQYGQQVQQG EKDRRRVLKD FSKMLDDQIE
     KIVLFLLEQQ GALASRIEKL GKQRAILAEQ PDISAIAELR EAYREVGLDL IKLLKFVDLN
     ATGIRKILKK FDKRFGYRFT DYYVTSRSNH PYSQLQQVFK HVGVGAVVGA LSRNLADLQE
     RQGSYLSIYD QPSTALKDPI IDMINSSVDK LTRSTNFLRF LGQHALIVGE ESPSTAEEEE
     IEDQKYHFMS LMLNLVNTFL YMVNTYIIVP TADDYSVSLG AASTVCGVVI GSMAVAQIFS
     SVYFSAWSNK SYFRPLIFSS IVLFLGNVCY AMAYDMKSLT VLIIGRLLCG MGSARAVNRR
     YISDCVPARI RMQASAGFVS ASALGMACGP ALAGLLQWKF KIYMVTFNQS TLPGWVMAVA
     WLLYLVWLWI SFKEPNRATE VNGTQQNPAS VQRADIEQLE NGLAQPLLRD SSKKDEDDDE
     EVDDSEEGTH DSRKPATSIG SAYRLLTPSV KVQLLIYFML KYAMEILLSE SSVITNHYFN
     WNTSAVAIFL AILGLTVLPV NAVVGTYISN MFEDRQLLMV SQITLLVGII FSFKITSTYS
     VVQYVVSALV TFVSAEVLEG VNLSLLSSVM SSRLSRGTYN GGLLSTEAGT LARVVADCTI
     TAAGYLGIGK LLNVTLLPSL VICAASIAST FLTYNSLF