ID   SPZ2B_ORYSJ             Reviewed;         404 AA.
AC   Q53KS9; A0A0P0Y0K3;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Serpin-Z2B;
DE   AltName: Full=OrysaZ2b;
GN   OrderedLocusNames=Os11g0239200, LOC_Os11g13540; ORFNames=OsJ_032137;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG   The rice chromosomes 11 and 12 sequencing consortia;
RT   "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT   genes and recent gene duplications.";
RL   BMC Biol. 3:20-20(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18060440; DOI=10.1007/s10142-007-0059-2;
RA   Roberts T.H., Hejgaard J.;
RT   "Serpins in plants and green algae.";
RL   Funct. Integr. Genomics 8:1-27(2008).
CC   -!- FUNCTION: Probable serine protease inhibitor. {ECO:0000250}.
CC   -!- DOMAIN: The reactive center loop (RCL) extends out from the body of the
CC       protein and directs binding to the target protease. The protease
CC       cleaves the serpin at the reactive site within the RCL, establishing a
CC       covalent linkage between the carboxyl group of the serpin reactive site
CC       and the serine hydroxyl of the protease. The resulting inactive serpin-
CC       protease complex is highly stable (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the serpin family. {ECO:0000305}.
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DR   EMBL; AC137993; AAX95890.1; -; Genomic_DNA.
DR   EMBL; AC145809; AAX92882.1; -; Genomic_DNA.
DR   EMBL; DP000010; ABA92263.1; -; Genomic_DNA.
DR   EMBL; AP014967; BAT13369.1; -; Genomic_DNA.
DR   EMBL; CM000148; EAZ17928.1; -; Genomic_DNA.
DR   RefSeq; XP_015616187.1; XM_015760701.1.
DR   AlphaFoldDB; Q53KS9; -.
DR   SMR; Q53KS9; -.
DR   STRING; 4530.OS11T0239200-00; -.
DR   PaxDb; Q53KS9; -.
DR   PRIDE; Q53KS9; -.
DR   EnsemblPlants; Os11t0239200-00; Os11t0239200-00; Os11g0239200.
DR   GeneID; 107275734; -.
DR   Gramene; Os11t0239200-00; Os11t0239200-00; Os11g0239200.
DR   KEGG; osa:107275734; -.
DR   eggNOG; KOG2392; Eukaryota.
DR   HOGENOM; CLU_023330_4_2_1; -.
DR   InParanoid; Q53KS9; -.
DR   OMA; IQHKQTG; -.
DR   OrthoDB; 1124079at2759; -.
DR   Proteomes; UP000000763; Chromosome 11.
DR   Proteomes; UP000007752; Chromosome 11.
DR   Proteomes; UP000059680; Chromosome 11.
DR   Genevisible; Q53KS9; OS.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.39.10; -; 1.
DR   Gene3D; 3.30.497.10; -; 1.
DR   InterPro; IPR023796; Serpin_dom.
DR   InterPro; IPR000215; Serpin_fam.
DR   InterPro; IPR036186; Serpin_sf.
DR   InterPro; IPR042178; Serpin_sf_1.
DR   InterPro; IPR042185; Serpin_sf_2.
DR   PANTHER; PTHR11461; PTHR11461; 1.
DR   Pfam; PF00079; Serpin; 1.
DR   SMART; SM00093; SERPIN; 1.
DR   SUPFAM; SSF56574; SSF56574; 1.
PE   2: Evidence at transcript level;
KW   Protease inhibitor; Reference proteome; Serine protease inhibitor.
FT   CHAIN           1..404
FT                   /note="Serpin-Z2B"
FT                   /id="PRO_0000334555"
FT   REGION          349..373
FT                   /note="RCL"
FT   SITE            363..364
FT                   /note="Reactive bond"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   404 AA;  43879 MW;  1A405188503BA948 CRC64;
     MEDDAGNCGG LTAFALRLAK RLADDGDNSN RNVVFSPVSL YAALALVASG ARGTTLDELV
     ALLGAASLDD LEESVRRAVE VGLADESESG GPRVSYACGV WHDERLALKP AYRAADFQRQ
     PKSSRKKINK WVSKATNKLI REILPDGSVH GGTALVLVNA IYFKGKWSNP FPRERTTTGK
     FHRLDGSSVD APFMSSREDQ YIGFYDGFKV LKLPYHRTMK NHGDGGDITP AILKHYGENV
     GLSMYIFLPD ARDGLPALVD KMAVASSGTA SSSFLRDHRP GRRRIKVGDL RVPRFKVSFY
     SEMNEVLKGM GIGAAFDVGK VDLSGMIDGE LVVVEKVMHR AVVEVNEEGT EAAAATACTM
     KFLCLTLTSP VDFVADHPFA FFVVEEKSDA VLFAGHVLDP TSLE