ID   SPZXB_ORYSJ             Reviewed;         405 AA.
AC   Q10GX0; B7F045; Q75H78;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Serpin-ZXB;
DE   AltName: Full=OrysaZxb;
GN   OrderedLocusNames=Os03g0610800, LOC_Os03g41438; ORFNames=OSJNBb0007E22.10;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16109971; DOI=10.1101/gr.3869505;
RG   The rice chromosome 3 sequencing consortium;
RA   Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA   Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA   Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA   Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA   Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA   Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA   Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA   Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA   Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA   Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA   O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA   Jin W., Lee H.R., Jiang J., Jackson S.;
RT   "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT   and diverged grass species.";
RL   Genome Res. 15:1284-1291(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [6]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18060440; DOI=10.1007/s10142-007-0059-2;
RA   Roberts T.H., Hejgaard J.;
RT   "Serpins in plants and green algae.";
RL   Funct. Integr. Genomics 8:1-27(2008).
CC   -!- FUNCTION: Probable serine protease inhibitor. {ECO:0000250}.
CC   -!- DOMAIN: The reactive center loop (RCL) extends out from the body of the
CC       protein and directs binding to the target protease. The protease
CC       cleaves the serpin at the reactive site within the RCL, establishing a
CC       covalent linkage between the carboxyl group of the serpin reactive site
CC       and the serine hydroxyl of the protease. The resulting inactive serpin-
CC       protease complex is highly stable (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the serpin family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAR00601.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC136972; AAR00601.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; DP000009; ABF97578.1; -; Genomic_DNA.
DR   EMBL; AP008209; BAF12566.1; -; Genomic_DNA.
DR   EMBL; AP014959; BAS85254.1; -; Genomic_DNA.
DR   EMBL; AK107194; BAG97992.1; -; mRNA.
DR   RefSeq; XP_015633126.1; XM_015777640.1.
DR   AlphaFoldDB; Q10GX0; -.
DR   SMR; Q10GX0; -.
DR   STRING; 4530.OS03T0610800-01; -.
DR   MEROPS; I04.032; -.
DR   PaxDb; Q10GX0; -.
DR   PRIDE; Q10GX0; -.
DR   EnsemblPlants; Os03t0610800-01; Os03t0610800-01; Os03g0610800.
DR   GeneID; 4333434; -.
DR   Gramene; Os03t0610800-01; Os03t0610800-01; Os03g0610800.
DR   KEGG; osa:4333434; -.
DR   eggNOG; KOG2392; Eukaryota.
DR   HOGENOM; CLU_023330_4_0_1; -.
DR   InParanoid; Q10GX0; -.
DR   OMA; KDVWRGL; -.
DR   OrthoDB; 1124079at2759; -.
DR   Proteomes; UP000000763; Chromosome 3.
DR   Proteomes; UP000059680; Chromosome 3.
DR   Genevisible; Q10GX0; OS.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.39.10; -; 1.
DR   Gene3D; 3.30.497.10; -; 1.
DR   InterPro; IPR023795; Serpin_CS.
DR   InterPro; IPR023796; Serpin_dom.
DR   InterPro; IPR000215; Serpin_fam.
DR   InterPro; IPR036186; Serpin_sf.
DR   InterPro; IPR042178; Serpin_sf_1.
DR   InterPro; IPR042185; Serpin_sf_2.
DR   PANTHER; PTHR11461; PTHR11461; 1.
DR   Pfam; PF00079; Serpin; 1.
DR   SMART; SM00093; SERPIN; 1.
DR   SUPFAM; SSF56574; SSF56574; 1.
DR   PROSITE; PS00284; SERPIN; 1.
PE   2: Evidence at transcript level;
KW   Protease inhibitor; Reference proteome; Serine protease inhibitor.
FT   CHAIN           1..405
FT                   /note="Serpin-ZXB"
FT                   /id="PRO_0000334566"
FT   REGION          354..378
FT                   /note="RCL"
FT   SITE            368..369
FT                   /note="Reactive bond"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   405 AA;  43343 MW;  5ADA2851D22F5E92 CRC64;
     MDATATDLRV SIAHQTRFAF RLAAALSSPR AHPAAGGAAG AGGSNVAFSP LSLHVALSLV
     AAGAGGATRD QLVSLLGVPG RGTAEGLHAF AEQVVQLVLA DSSPAGGPRV AFADGVFIDS
     SLSLMKSFKD VAVGKYKAET HSVDFQTKAA EVASQVNSWV DRVTSGLIKE ILPPGSVDHT
     TRLVLGNALY FKGAWTEKFD ASKTKDGEFR LLDGKSVLAP FMSTSKKQYL SSYDSLKVLK
     LPYQKGRDLR QFSMYILLPE AQDGLWSLAA KLNSEPEFLE KRIPTRQVTV GKFKLPKFKI
     SFGFEASDLL KILGLQLPFS SKADLTGMVG SPERHNLFVS SLFHKSFVQV DEEGTEAAAA
     SAAVVSFRSA PVTVDFVADH PFLFLIREDM TGVVLFIGHV VNPLL