SQS1_CANAL
ID SQS1_CANAL Reviewed; 705 AA.
AC Q59UG4; A0A1D8PSE6; Q59UL7;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2005, sequence version 1.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=Protein SQS1;
GN Name=SQS1; OrderedLocusNames=CAALFM_CR03230WA;
GN ORFNames=CaO19.2400, CaO19.9936;
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC -!- FUNCTION: May be involved in splicing. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SQS1 family. {ECO:0000305}.
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DR EMBL; CP017630; AOW31061.1; -; Genomic_DNA.
DR RefSeq; XP_713233.1; XM_708140.1.
DR AlphaFoldDB; Q59UG4; -.
DR SMR; Q59UG4; -.
DR STRING; 237561.Q59UG4; -.
DR PRIDE; Q59UG4; -.
DR GeneID; 3645127; -.
DR KEGG; cal:CAALFM_CR03230WA; -.
DR CGD; CAL0000180348; orf19.9937.
DR VEuPathDB; FungiDB:CR_03230W_A; -.
DR eggNOG; KOG0154; Eukaryota.
DR HOGENOM; CLU_021974_1_0_1; -.
DR InParanoid; Q59UG4; -.
DR OrthoDB; 941249at2759; -.
DR PRO; PR:Q59UG4; -.
DR Proteomes; UP000000559; Chromosome R.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR CDD; cd02646; R3H_G-patch; 1.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR034082; R3H_G-patch.
DR Pfam; PF01585; G-patch; 1.
DR SMART; SM00443; G_patch; 1.
DR PROSITE; PS50174; G_PATCH; 1.
PE 3: Inferred from homology;
KW Cytoplasm; mRNA processing; mRNA splicing; Nucleus; Reference proteome.
FT CHAIN 1..705
FT /note="Protein SQS1"
FT /id="PRO_0000324994"
FT DOMAIN 530..594
FT /note="R3H"
FT DOMAIN 662..705
FT /note="G-patch"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT REGION 1..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 152..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 287..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 398..439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 616..648
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..192
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..241
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..259
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 287..321
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..439
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 705 AA; 80496 MW; DC0F8099EDD8E7B7 CRC64;
MPKRGNRRRR GGTGGSGGGR GGRGGSRGRG GGRRTPSGAN RGRHPSRGNK NRSPRTITQY
GDLMDDDNIF IPKTMSEVAS NMGRRKYGGM FEEIEYTESH QEDLMSRQLR NRPVEFVKAK
EVYDPNVILY KLAKLNNKDD GIDIAVQSIS LDDSENESST NKVDISSSEE IEESGDEYED
EQDDEDDWDE EELHNEITTK LEALEEAMNN VSSDTESEQS VSHIEEEDEK VESHIPEPDL
SAEVDEPLQE IDESENENQM ESEVGTNTNT QDIETLDIII DLPSNKVESH MSHSLPQKFK
TPSSPDDDND DNNNNSTPES EPEYGYLEED YEFDVSKIEV SNVRFGIENQ YHIKCMELTG
SIDEYIWIDE NDVIEYVLDN GVKEHRLNKF LSFITKGMID EQEPEPEPEV YISDSNSEEE
EEEEDDYNSE QDDYPYDSDD NLEDLIAYSK TSTQGLIPFE DRDFSNNIPS KKRQTFDHLD
FDDDGELQDS LIRQLNNYKA NKKLKKHQWE QQKLEESILH HDMLIKYPVS LHIKDIKSEF
DQLLKDESRQ SMSFPTLDTH GHKTIKNLAD CYHMSVIKSG KQGIRKYLKI VKNKATFKYY
PNYERINRIL RGRPIFHRID QKPQHKKGEK SKSKSSRGDA SSSRARFKEG DIVGAEAPEI
GSSNLGRQML EKLGWIQGQG LGVDGNKGIN EPILAKVKTS KTGIK
