SQS1_CANGA
ID SQS1_CANGA Reviewed; 808 AA.
AC Q6FP19;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 84.
DE RecName: Full=Protein SQS1;
GN Name=SQS1; OrderedLocusNames=CAGL0J07326g;
OS Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS Y-65) (Yeast) (Torulopsis glabrata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC Nakaseomyces/Candida clade.
OX NCBI_TaxID=284593;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: May be involved in splicing. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SQS1 family. {ECO:0000305}.
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DR EMBL; CR380956; CAG60976.1; -; Genomic_DNA.
DR RefSeq; XP_448025.1; XM_448025.1.
DR AlphaFoldDB; Q6FP19; -.
DR STRING; 5478.XP_448025.1; -.
DR PRIDE; Q6FP19; -.
DR EnsemblFungi; CAG60976; CAG60976; CAGL0J07326g.
DR GeneID; 2889588; -.
DR KEGG; cgr:CAGL0J07326g; -.
DR CGD; CAL0133348; CAGL0J07326g.
DR VEuPathDB; FungiDB:CAGL0J07326g; -.
DR eggNOG; KOG0154; Eukaryota.
DR HOGENOM; CLU_021974_1_0_1; -.
DR InParanoid; Q6FP19; -.
DR OMA; PVFMRID; -.
DR Proteomes; UP000002428; Chromosome J.
DR GO; GO:0030686; C:90S preribosome; IEA:EnsemblFungi.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IEA:EnsemblFungi.
DR GO; GO:0030688; C:preribosome, small subunit precursor; IEA:EnsemblFungi.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0030490; P:maturation of SSU-rRNA; IEA:EnsemblFungi.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:EnsemblFungi.
DR GO; GO:0051096; P:positive regulation of helicase activity; IEA:EnsemblFungi.
DR CDD; cd02646; R3H_G-patch; 1.
DR Gene3D; 3.30.1370.50; -; 1.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR036867; R3H_dom_sf.
DR InterPro; IPR034082; R3H_G-patch.
DR Pfam; PF01585; G-patch; 1.
DR SMART; SM00443; G_patch; 1.
DR SUPFAM; SSF82708; SSF82708; 1.
DR PROSITE; PS50174; G_PATCH; 1.
PE 3: Inferred from homology;
KW Cytoplasm; mRNA processing; mRNA splicing; Nucleus; Reference proteome.
FT CHAIN 1..808
FT /note="Protein SQS1"
FT /id="PRO_0000324995"
FT DOMAIN 621..683
FT /note="R3H"
FT DOMAIN 748..795
FT /note="G-patch"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT REGION 1..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 151..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 485..529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 764..808
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..34
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 154..180
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 485..518
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 789..808
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 808 AA; 92551 MW; 30A3BCBE9AACC555 CRC64;
MAKRHKHFES RGGFRKKRGG GRGSQRGRGS KRGRGGRFRG FEETERSASE PGAWLNSSVP
LGDGDLSNPD MMVDNYRPRK HISQDTITDH YFGRKSSLKL NSMRMAGLRH NDWRDPNNGN
SASFRKRPIE FIKANCTYDP SRDLILQLAN RSKNQESKEP EEDANKCSEY AEHSEKDMEI
DTAATENDAN ISYDESDTDQ EIGNFNHSIE NSKHNNNISE CDITAVTDQE LFFVDEEGMD
ISQKPTKVVH ITEHEKKMGS NVEFHNVLTV GKVEISLNQD ENDEVYVDRK PTAKYHPFHN
YISNVIERMQ EEENIDSDDF EDEDDIYLDN SGNDMPETEL DQDEIIDLQR HDDKDHAVQT
CAIPTNTLSN DLDTLHITES NDDRITINNH NMDSTVETDK EKDPEFGFLE EDYAVNTSEV
IVDNIRLGLN DNSYFLKCYR FFGDYSFHWI DQEAFVSFLT EDLELPMNRV GAYLAYVKNS
LVPDETPPSP TYSDIPFSDT SNESDEDNAL PNVDAVSSCS NDDEDEELGD DVDDLVSYSL
KYANSRNIDY ETRALEFTGK GKKKKLLVNE QLDLDNETME TLQAKLSKRM ENKAKKRRLK
EDFIDKENMN SDDLFLKYPY GFHVQNIRDE FELFLTRNKD RMSFPPLDPH GNKVITKFAT
CYNIKSSKVG KGNHTHIMVE KVKKTKWSRP NYNMVLQLTR QRPVFMRIDV RRPKEDAIKE
NSGRRGPTAK FHVKEGEVVG ENAPEIGQDN IGRRMLEKLG WSSGEGLGAH GNKGISIPVM
ARVKKSKSGL RHSKEDEDTG RSSSFRKK
