SQS1_DEBHA
ID SQS1_DEBHA Reviewed; 808 AA.
AC Q6BYP9;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 16-DEC-2008, sequence version 2.
DT 25-MAY-2022, entry version 70.
DE RecName: Full=Protein SQS1;
GN Name=SQS1; OrderedLocusNames=DEHA2A07810g;
OS Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX NCBI_TaxID=284592;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: May be involved in splicing. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SQS1 family. {ECO:0000305}.
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DR EMBL; CR382133; CAG84626.2; -; Genomic_DNA.
DR RefSeq; XP_456670.2; XM_456670.1.
DR AlphaFoldDB; Q6BYP9; -.
DR SMR; Q6BYP9; -.
DR STRING; 4959.XP_456670.2; -.
DR EnsemblFungi; CAG84626; CAG84626; DEHA2A07810g.
DR GeneID; 2899654; -.
DR KEGG; dha:DEHA2A07810g; -.
DR VEuPathDB; FungiDB:DEHA2A07810g; -.
DR eggNOG; KOG0154; Eukaryota.
DR HOGENOM; CLU_021974_1_0_1; -.
DR InParanoid; Q6BYP9; -.
DR OMA; PVFMRID; -.
DR OrthoDB; 962410at2759; -.
DR Proteomes; UP000000599; Chromosome A.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR CDD; cd02646; R3H_G-patch; 1.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR034082; R3H_G-patch.
DR Pfam; PF01585; G-patch; 1.
DR SMART; SM00443; G_patch; 1.
DR PROSITE; PS50174; G_PATCH; 1.
PE 3: Inferred from homology;
KW Cytoplasm; mRNA processing; mRNA splicing; Nucleus; Reference proteome.
FT CHAIN 1..808
FT /note="Protein SQS1"
FT /id="PRO_0000324996"
FT DOMAIN 629..692
FT /note="R3H"
FT DOMAIN 765..808
FT /note="G-patch"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 143..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 393..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 593..612
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 709..763
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 783..808
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..225
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..240
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..270
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 285..306
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..425
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 714..748
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 808 AA; 91295 MW; 6C4DE0F32F1D7CAD CRC64;
MPKRGGRKSH PKKDKGGGGG GSNFGRFKTN KNKKKTGMGS SKNHGTPRST NIDIPELMDL
DDNVYIPEID TKVSQSSMKN LSRRPGRRHL YEEVGYTDKH IEDTLRQPLR NRPIEFVKAK
QVYDPSADLF KKLGKSGIPK VHQDLLDSMN SPPSQEAHVP ESPILDILSE ESEDDAIDEV
VAHLASSNTS LDSDLVGRGE ISKTNDEGES DDVEEEIEEE VEDENESEHN EHRGIESQTE
SEQDEQDEQD EQDEAEEVEE EEEEAFIIDD TGDAEILKDH NPVKPQTSLL IQSKLPKSST
QNDIDNIGGG LDYDPVLNIG KVSLQTKRDE NGQSTTELMS VNQLNKISTK GFIDEKKMLP
NMEKNVSDIS DDDFGGYKDY IAQVMRDGKL EVDSDEYESE TNFDIMASSS DNDDDDEDND
EGEKDPSEIE YGFLPEDYEF DVSQVSISNV RFGINNQLYT KCAELTGSDD QFLWIDEDDL
VDYVLSKGVR EHRLNSFMKF ITKGLIDEEA IEVPNYSDVY ISETSEDEEE GANSEDENLA
AMIAFTKSQQ QSFMDLDIPS TERLKTKGKG KKKQLDLDRM QLDIDMRESL QDQYQVHRQA
KRSKKQRRED ARYEGGIAKH DLLVKYPYSL HIKDICYEFE TFLHDTSRDS MNFPPLDPHG
NKTVIKISNF YNMKSLKCGT GLKSFVKVSK NRKTFHYLPR YDQIGNVSRQ RPIFNRIDQK
RPKDEITRSD GNSKKDRSRG RNKSESSAQS REGDIVGASA PEIGTNNIGR KLLEKLGWSK
GEGLGAHGNK GISEPVVAKI KKSKTGLK
