SQS1_LODEL
ID SQS1_LODEL Reviewed; 792 AA.
AC A5DSB5;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 03-AUG-2022, entry version 59.
DE RecName: Full=Protein SQS1;
GN Name=SQS1; ORFNames=LELG_00251;
OS Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC Lodderomyces.
OX NCBI_TaxID=379508;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL
RC YB-4239;
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA Birren B.W., Kellis M., Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- FUNCTION: May be involved in splicing. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SQS1 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CH981524; EDK42073.1; -; Genomic_DNA.
DR RefSeq; XP_001527731.1; XM_001527681.1.
DR AlphaFoldDB; A5DSB5; -.
DR SMR; A5DSB5; -.
DR STRING; 379508.A5DSB5; -.
DR EnsemblFungi; EDK42073; EDK42073; LELG_00251.
DR GeneID; 5234878; -.
DR KEGG; lel:LELG_00251; -.
DR VEuPathDB; FungiDB:LELG_00251; -.
DR eggNOG; KOG0154; Eukaryota.
DR HOGENOM; CLU_021974_1_0_1; -.
DR InParanoid; A5DSB5; -.
DR OMA; PVFMRID; -.
DR OrthoDB; 941249at2759; -.
DR Proteomes; UP000001996; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR CDD; cd02646; R3H_G-patch; 1.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR034082; R3H_G-patch.
DR Pfam; PF01585; G-patch; 1.
DR SMART; SM00443; G_patch; 1.
DR PROSITE; PS50174; G_PATCH; 1.
PE 3: Inferred from homology;
KW Cytoplasm; mRNA processing; mRNA splicing; Nucleus; Reference proteome.
FT CHAIN 1..792
FT /note="Protein SQS1"
FT /id="PRO_0000324998"
FT DOMAIN 619..683
FT /note="R3H"
FT DOMAIN 750..792
FT /note="G-patch"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 139..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 225..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 343..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 494..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 709..734
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..47
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..206
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..260
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..313
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 348..364
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 494..518
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 709..723
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 792 AA; 90793 MW; A88B1EF762AE1608 CRC64;
MPKRGNRRTR GSRGGSRGGS RNLLKNRTRG NKRKSPSSNT YNRLSSSQYQ ELMDLDSIYI
PNGEMAEVGR NMGRRRYGKL AEEAAYTESH RYEDFASKTF RNRPIEFIKA KEVYDPNVIL
HKLTQEKKTQ YGDIIDEEFK SISLDDSEAD SEADDDDEEE EEEEEEEKDG QEMENENETD
DANEEADEQS SELWNDEEEG DSQEDWDEEE LRKVLDKKLV QLQKELDLEQ DVGIVEKNEK
DIIDKEDKES DVDDSILNAD KENSEQFVNI GKNQSEIESE DEDGDEEEEQ DLDENNDFED
DSDDDLDDAS IEDINGEEFA KQNDVSSISY LDENNIYSEK LSRDESLDSI PGSKNVDNSS
SLEEITVKSK PKDLVKNATN NFINCNERTG KDKPESEPEY GFLEEDYEFD VSKIEVSNVR
FGISNQYYVK CAELTGTTVD EFFWFDEEDV IDYVLANGVK EHRLAKFLSF VTKGMVGGNE
SESQEDLDAF TIDVNGLDDD DESDDDEDDD EDEDENKFAS GQDDYPYDSE DGLEDLIAYT
RNSTQGLVPM LDRDFSRNIP AKSRSTFDDL DIDPDLQSSL TRQLKNYNHN KREKRKARKD
REVEEAVLRN DMLIKYPEKI LIKEIRAEFE ALLKDESRHS MSFPTLDSHG HHTIKNMADC
YHMTTDKCGK QGVRHYLKVS KTKSTFKYFP NYKRVNAIMR GRPIFHRIDR KPNPKDKKTK
TISGRGSDSG GRAKFKEGDI VGAEAPEIDQ NNLGRQMLER LGWSKGMGLG LSGRGINEPI
VAKVKMSKTG IK
