ID   SQS1_YARLI              Reviewed;         812 AA.
AC   Q6C233;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Protein SQS1;
GN   Name=SQS1; OrderedLocusNames=YALI0F11253g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: May be involved in splicing. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SQS1 family. {ECO:0000305}.
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DR   EMBL; CR382132; CAG78086.1; -; Genomic_DNA.
DR   RefSeq; XP_505279.1; XM_505279.1.
DR   AlphaFoldDB; Q6C233; -.
DR   STRING; 4952.CAG78086; -.
DR   EnsemblFungi; CAG78086; CAG78086; YALI0_F11253g.
DR   GeneID; 2907966; -.
DR   KEGG; yli:YALI0F11253g; -.
DR   VEuPathDB; FungiDB:YALI0_F11253g; -.
DR   HOGENOM; CLU_347551_0_0_1; -.
DR   InParanoid; Q6C233; -.
DR   OMA; IDWIRSA; -.
DR   Proteomes; UP000001300; Chromosome F.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   InterPro; IPR000467; G_patch_dom.
DR   Pfam; PF01585; G-patch; 1.
DR   SMART; SM00443; G_patch; 1.
DR   PROSITE; PS50174; G_PATCH; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; mRNA processing; mRNA splicing; Nucleus; Reference proteome.
FT   CHAIN           1..812
FT                   /note="Protein SQS1"
FT                   /id="PRO_0000325002"
FT   DOMAIN          636..700
FT                   /note="R3H"
FT   DOMAIN          769..812
FT                   /note="G-patch"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT   REGION          17..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          188..284
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          409..435
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          511..540
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        26..41
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        188..241
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        270..284
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        413..435
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        512..534
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   812 AA;  91279 MW;  6D788428F10CA748 CRC64;
     MPTGYHNFCD DELDESINFN YNRKPSQPKD YDDDSRTSGR TTPKRARGGR GRGSGDRGGR
     GGSRGRGGNG GSSRGGKKNG WRDEKPSLLS SILNSRQHAS ENREHMFNKS LRGAEFITFI
     KSAEVYDPSK LLKDVGVTVE EANVVNEVED IHIIVPEVIP EVQDVTGADA QLEDQESEDE
     EVVTTITETY ADDGDNQEDD DDEMLVDGNG QLVDDYDDDE DDDDEDDEID EEVDDDLIAD
     ENAVDVSTLQ DAINEVANDT INDDRKEEDP SEGSEADDEE DEAAEFVMDT EGDPDMVDME
     FMETDFAYLN KKKRAEKSRT PLTSSTAVIS DRPVASVSAD TTLVGSVASK KRHNADPRAV
     DIPEYNSDID PEVLKDYIES IKNEDEGSDA ENIDWIRSAL GTQLGGTEQY YVDSDDSEND
     DFDDDDEDDE EEYEWPENGT VGCIRNIVAT RAASQGYQFM VEHTLDADME EWWNEDLIRD
     SVAEHLGVSV SELPDEAYRW YVTRLGGDIE DPDLSEEGIN YSDYYDDSDE DEKAREASEM
     DSLIQSLIDD EVDDRKALMD HGYTPPMTKS RGKNQVPNFG VNDPELQAQL EKHWVNSRAA
     KRAKREQRQA MRKQGMFTKE FKQGGIIPLH AKYPILMTVE EARKEIEIFI NAPNKPMVLD
     FPPMGAEFRS VLKKLSACYH LKPDIHGVQK SKHVSMLRTS RTSCHNNNYI QKFHDKFPKK
     FKLVIRNAKY STEQYLYETK HQKGSKRSAV RVHNREGEIV GHEAPAIDDS NIGRLLLQKM
     GWTTGEGLGA QSRGISEPII AKVKISKRGI GA