ID   SQUT_SALTI              Reviewed;         292 AA.
AC   Q8Z2T5;
DT   28-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Sulfofructosephosphate aldolase {ECO:0000255|HAMAP-Rule:MF_01912};
DE            Short=SFP aldolase {ECO:0000255|HAMAP-Rule:MF_01912};
DE            EC=4.1.2.57 {ECO:0000255|HAMAP-Rule:MF_01912};
GN   Name=yihT; OrderedLocusNames=STY3856, t3599;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: Cleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form
CC       dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA).
CC       {ECO:0000255|HAMAP-Rule:MF_01912}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=6-deoxy-6-sulfo-D-fructose 1-phosphate = (2S)-3-
CC         sulfolactaldehyde + dihydroxyacetone phosphate; Xref=Rhea:RHEA:40515,
CC         ChEBI:CHEBI:57642, ChEBI:CHEBI:77134, ChEBI:CHEBI:90109; EC=4.1.2.57;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01912};
CC   -!- SIMILARITY: Belongs to the aldolase LacD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01912}.
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DR   EMBL; AL513382; CAD09604.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO71102.1; -; Genomic_DNA.
DR   RefSeq; NP_458029.1; NC_003198.1.
DR   RefSeq; WP_001067413.1; NZ_WSUR01000010.1.
DR   AlphaFoldDB; Q8Z2T5; -.
DR   SMR; Q8Z2T5; -.
DR   STRING; 220341.16504716; -.
DR   EnsemblBacteria; AAO71102; AAO71102; t3599.
DR   KEGG; stt:t3599; -.
DR   KEGG; sty:STY3856; -.
DR   PATRIC; fig|220341.7.peg.3936; -.
DR   eggNOG; COG3684; Bacteria.
DR   HOGENOM; CLU_083300_0_0_6; -.
DR   OMA; KDITRPS; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0061595; F:6-deoxy-6-sulfofructose-1-phosphate aldolase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:1902777; P:6-sulfoquinovose(1-) catabolic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.20.20.70; -; 1.
DR   HAMAP; MF_01912; SFP_aldolase; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002915; DeoC/FbaB/LacD_aldolase.
DR   InterPro; IPR017291; SFP_aldolase_YihT.
DR   Pfam; PF01791; DeoC; 1.
DR   PIRSF; PIRSF037840; Aldolase_YihT; 1.
DR   SMART; SM01133; DeoC; 1.
PE   3: Inferred from homology;
KW   Lyase.
FT   CHAIN           1..292
FT                   /note="Sulfofructosephosphate aldolase"
FT                   /id="PRO_0000203971"
SQ   SEQUENCE   292 AA;  31867 MW;  50F538F48506EF34 CRC64;
     MNNYTIKDIT RASGGFAMLA VDQREAMRLM FAAAGAKTPV ADSVLTDFKV NAAKILSPYA
     SAVLLDQQFC YRQAVEQNAV AKSCAMIVAA DDFIPGNGIP VDNVVIDKKI NAQAVKRDGA
     KALKLLVLWR SDEDAQQRLD MVKEFNELCH SNGLLSIIEP VVRPPRCGDK FDREQAIIDA
     AKELGDSGAD LYKVEMPLYG KGARSDLLTA SQRLNGHINM PWVILSSGVD EKLFPRAVRV
     AMEAGASGFL AGRAVWSSVI GLPDTELMLR DVSAPKLQRL GEIVDEMMAK RR