ID   SQUT_SHIFL              Reviewed;         292 AA.
AC   Q83PF0;
DT   28-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=Sulfofructosephosphate aldolase {ECO:0000255|HAMAP-Rule:MF_01912};
DE            Short=SFP aldolase {ECO:0000255|HAMAP-Rule:MF_01912};
DE            EC=4.1.2.57 {ECO:0000255|HAMAP-Rule:MF_01912};
GN   Name=yihT; OrderedLocusNames=SF3953, S3793;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: Cleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form
CC       dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA).
CC       {ECO:0000255|HAMAP-Rule:MF_01912}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=6-deoxy-6-sulfo-D-fructose 1-phosphate = (2S)-3-
CC         sulfolactaldehyde + dihydroxyacetone phosphate; Xref=Rhea:RHEA:40515,
CC         ChEBI:CHEBI:57642, ChEBI:CHEBI:77134, ChEBI:CHEBI:90109; EC=4.1.2.57;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01912};
CC   -!- SIMILARITY: Belongs to the aldolase LacD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01912}.
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DR   EMBL; AE005674; AAN45388.1; -; Genomic_DNA.
DR   EMBL; AE014073; AAP18812.1; -; Genomic_DNA.
DR   RefSeq; NP_709681.1; NC_004337.2.
DR   RefSeq; WP_001046454.1; NZ_WPGW01000092.1.
DR   AlphaFoldDB; Q83PF0; -.
DR   SMR; Q83PF0; -.
DR   STRING; 198214.SF3953; -.
DR   EnsemblBacteria; AAN45388; AAN45388; SF3953.
DR   EnsemblBacteria; AAP18812; AAP18812; S3793.
DR   GeneID; 1023605; -.
DR   KEGG; sfl:SF3953; -.
DR   KEGG; sfx:S3793; -.
DR   PATRIC; fig|198214.7.peg.4658; -.
DR   HOGENOM; CLU_083300_0_0_6; -.
DR   OMA; KDITRPS; -.
DR   OrthoDB; 1560751at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0061595; F:6-deoxy-6-sulfofructose-1-phosphate aldolase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:1902777; P:6-sulfoquinovose(1-) catabolic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.20.20.70; -; 1.
DR   HAMAP; MF_01912; SFP_aldolase; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002915; DeoC/FbaB/LacD_aldolase.
DR   InterPro; IPR017291; SFP_aldolase_YihT.
DR   Pfam; PF01791; DeoC; 1.
DR   PIRSF; PIRSF037840; Aldolase_YihT; 1.
DR   SMART; SM01133; DeoC; 1.
PE   3: Inferred from homology;
KW   Lyase; Reference proteome.
FT   CHAIN           1..292
FT                   /note="Sulfofructosephosphate aldolase"
FT                   /id="PRO_0000203973"
SQ   SEQUENCE   292 AA;  32013 MW;  5789C133E43F447F CRC64;
     MNKYTINDIT RASGGFAMLA VDQREAMRMM FAAAGAPAPV ADSVLTDFKV NAAKALSPYA
     SAILVDQQFC YRQVVEQNAI AKSCAMIVAA DEFIPGNGIP VDSVVIDRKI NPLQIKQDGG
     KALKLLVLWR SDEDAQQRLD MVKEFNELCH SHGLVSIIEP VVRPPRRGDK FDREQAIIDA
     AKELGDSGAD LYKVEMPLYG KGPQQELLCA SQRLNDHINM PWVILSSSVD EKLFPRAVRV
     AMTAGASGFL AGRAVWASVV GLPDNELMLR DVCAPKLQQL GDIVDEMMAK RR