ID   SR1IP_RAT               Reviewed;         153 AA.
AC   Q5RJP9;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Protein SREK1IP1;
DE   AltName: Full=SFRS12-interacting protein 1;
DE   AltName: Full=SREK1-interacting protein 1;
GN   Name=Srek1ip1; Synonyms=Sfrs12ip1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=15456940; DOI=10.1385/jmn:24:2:269;
RA   Heese K., Fujita M., Akatsu H., Yamamoto T., Kosaka K., Nagai Y.,
RA   Sawada T.;
RT   "The splicing regulatory protein p18SRP is down-regulated in Alzheimer's
RT   disease brain.";
RL   J. Mol. Neurosci. 24:269-276(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Possible splicing regulator involved in the control of
CC       cellular survival. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with SREK1/SFRS12. {ECO:0000250}.
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DR   EMBL; AY236996; AAP69947.1; -; mRNA.
DR   EMBL; BC086553; AAH86553.1; -; mRNA.
DR   RefSeq; NP_001008374.1; NM_001008373.1.
DR   AlphaFoldDB; Q5RJP9; -.
DR   STRING; 10116.ENSRNOP00000064069; -.
DR   PaxDb; Q5RJP9; -.
DR   GeneID; 361888; -.
DR   KEGG; rno:361888; -.
DR   UCSC; RGD:1305356; rat.
DR   CTD; 285672; -.
DR   RGD; 1305356; Srek1ip1.
DR   eggNOG; KOG2985; Eukaryota.
DR   InParanoid; Q5RJP9; -.
DR   OrthoDB; 1601271at2759; -.
DR   PRO; PR:Q5RJP9; -.
DR   Proteomes; UP000002494; Unplaced.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   InterPro; IPR001878; Znf_CCHC.
DR   PROSITE; PS50158; ZF_CCHC; 1.
PE   2: Evidence at transcript level;
KW   Metal-binding; mRNA processing; mRNA splicing; Phosphoprotein;
KW   Reference proteome; Zinc; Zinc-finger.
FT   CHAIN           1..153
FT                   /note="Protein SREK1IP1"
FT                   /id="PRO_0000311924"
FT   ZN_FING         13..30
FT                   /note="CCHC-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT   REGION          44..153
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        58..81
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        94..109
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        110..142
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         52
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8N9Q2"
FT   MOD_RES         96
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q4V9W2"
FT   MOD_RES         97
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q4V9W2"
SQ   SEQUENCE   153 AA;  18049 MW;  D415AAAF9DD0764A CRC64;
     MAVPGCNKDN VRAGCRKCGY PGHLTFECRN FLRVDPKRDI VLDVSSTSSE DSDEESEELN
     KLQALQEKRI NEEEEKKKEK SREKIKLKKK RKRSNSSTTE EDSSKQKKQK YQKKEKKKEK
     KNKSKKGKHH KKEKKKRKKE KRSSPNRSEV TKK