ID   SRA18_CAEEL             Reviewed;         340 AA.
AC   O18689;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Serpentine receptor class alpha-18;
DE            Short=Protein sra-18;
GN   Name=sra-18; ORFNames=F28C12.2;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the nematode receptor-like protein sra family.
CC       {ECO:0000305}.
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DR   EMBL; Z93380; CAB07596.1; -; Genomic_DNA.
DR   PIR; T21472; T21472.
DR   RefSeq; NP_493214.1; NM_060813.1.
DR   AlphaFoldDB; O18689; -.
DR   BioGRID; 49833; 1.
DR   PaxDb; O18689; -.
DR   EnsemblMetazoa; F28C12.2.1; F28C12.2.1; WBGene00005044.
DR   GeneID; 185054; -.
DR   KEGG; cel:CELE_F28C12.2; -.
DR   UCSC; F28C12.2; c. elegans.
DR   CTD; 185054; -.
DR   WormBase; F28C12.2; CE09749; WBGene00005044; sra-18.
DR   eggNOG; ENOG502THAY; Eukaryota.
DR   GeneTree; ENSGT00970000195862; -.
DR   HOGENOM; CLU_070413_0_0_1; -.
DR   InParanoid; O18689; -.
DR   PhylomeDB; O18689; -.
DR   PRO; PR:O18689; -.
DR   Proteomes; UP000001940; Chromosome I.
DR   Bgee; WBGene00005044; Expressed in adult organism.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR   GO; GO:0007606; P:sensory perception of chemical stimulus; IEA:InterPro.
DR   InterPro; IPR000344; 7TM_GPCR_serpentine_rcpt_Sra.
DR   Pfam; PF02117; 7TM_GPCR_Sra; 1.
DR   PRINTS; PR00697; TMPROTEINSRA.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..340
FT                   /note="Serpentine receptor class alpha-18"
FT                   /id="PRO_0000104481"
FT   TRANSMEM        29..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        109..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        149..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        198..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        249..269
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        285..305
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   340 AA;  39225 MW;  226508E8DCD745F9 CRC64;
     MNKTAEELDS RNCASESLTN ALISITMKFN FIFIITVVLI SYCFTWLAIQ ALWKHNIFSN
     STRLILIVCL LNSVVHQTTM LETRITQAYR SVVYDSEPCK LLFRSSDCVF ELYLYYPTGY
     FSTYSVFSLT FDRLISHYKS RYYHMHQYFI ATSLLVLQLL LTMFSFYIVF YGVSLAGYVP
     MCNFRPELTV YYGAINNVRT GVMVSCIIVT MFVYYVCVKS EKQIQKCSYS PGERYSAYEN
     VTTSQSICIS IVLQFSCIMI SSFGSNLLIH ITSKTTVSEE VFYAIVSFLP GVTYANLCLP
     LVIYFKTKLT TRNRKNRIAV MTSMYGDAGE HIDRLKRSWE