ID   SRA21_CAEEL             Reviewed;         339 AA.
AC   O18690;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Serpentine receptor class alpha-21;
DE            Short=Protein sra-21;
GN   Name=sra-21; ORFNames=F28C12.5;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the nematode receptor-like protein sra family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; Z93380; CAB07597.1; -; Genomic_DNA.
DR   PIR; T21473; T21473.
DR   RefSeq; NP_493217.1; NM_060816.1.
DR   AlphaFoldDB; O18690; -.
DR   PaxDb; O18690; -.
DR   EnsemblMetazoa; F28C12.5.1; F28C12.5.1; WBGene00005047.
DR   GeneID; 185057; -.
DR   KEGG; cel:CELE_F28C12.5; -.
DR   UCSC; F28C12.5; c. elegans.
DR   CTD; 185057; -.
DR   WormBase; F28C12.5; CE09752; WBGene00005047; sra-21.
DR   eggNOG; ENOG502THAY; Eukaryota.
DR   GeneTree; ENSGT00970000195862; -.
DR   HOGENOM; CLU_070413_0_0_1; -.
DR   InParanoid; O18690; -.
DR   PhylomeDB; O18690; -.
DR   PRO; PR:O18690; -.
DR   Proteomes; UP000001940; Chromosome I.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR   GO; GO:0007606; P:sensory perception of chemical stimulus; IEA:InterPro.
DR   InterPro; IPR000344; 7TM_GPCR_serpentine_rcpt_Sra.
DR   Pfam; PF02117; 7TM_GPCR_Sra; 1.
DR   PRINTS; PR00697; TMPROTEINSRA.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..339
FT                   /note="Serpentine receptor class alpha-21"
FT                   /id="PRO_0000104483"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        199..219
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        250..270
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        282..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   339 AA;  38746 MW;  0B79A8AFB8724085 CRC64;
     MSQLTAEELD SQKCASEGLT SVLTSITMKF NFLFITTVIL LSYCFTWLAI RALWKNNIFS
     NSTRLILIAC LLNSVVHQTT MLESRMRQTY RSFVFASEPC NLLYRSSDCV FELHSYYLTG
     YFSTYSVCSL AFDRLVSHYK SKFYHTHQYF IAVSLLVLQL LLTLVSFYIA YYGVHLAGYV
     PVCIHYPRLA VHYSTVNTVR TVVMVCCLVV TGFIYYLSVK SEKQIQKSSY SPGKRYTAYE
     NVTTSQSVCI LIVLKLFCNM LSSIGINLLL LMGEVVSEGT FVLVALFLPG VTYANLCLPL
     VIYFKTKLII RNRKFRIAVM TSMYGDAGEH IDRLKKSWE