ID   SRA22_CAEEL             Reviewed;         339 AA.
AC   O17846; O18055;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 3.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Serpentine receptor class alpha-22;
DE            Short=Protein sra-22;
GN   Name=sra-22; ORFNames=F28C12.7;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the nematode receptor-like protein sra family.
CC       {ECO:0000305}.
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DR   EMBL; Z93380; CAB07602.2; -; Genomic_DNA.
DR   EMBL; Z81587; CAB07602.2; JOINED; Genomic_DNA.
DR   PIR; T21478; T21478.
DR   RefSeq; NP_493218.2; NM_060817.2.
DR   AlphaFoldDB; O17846; -.
DR   PaxDb; O17846; -.
DR   EnsemblMetazoa; F28C12.7.1; F28C12.7.1; WBGene00005048.
DR   GeneID; 185059; -.
DR   KEGG; cel:CELE_F28C12.7; -.
DR   UCSC; F28C12.7; c. elegans.
DR   CTD; 185059; -.
DR   WormBase; F28C12.7; CE33386; WBGene00005048; sra-22.
DR   eggNOG; ENOG502THAY; Eukaryota.
DR   GeneTree; ENSGT00970000195862; -.
DR   HOGENOM; CLU_070413_0_0_1; -.
DR   InParanoid; O17846; -.
DR   PhylomeDB; O17846; -.
DR   PRO; PR:O17846; -.
DR   Proteomes; UP000001940; Chromosome I.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR   GO; GO:0007606; P:sensory perception of chemical stimulus; IEA:InterPro.
DR   InterPro; IPR000344; 7TM_GPCR_serpentine_rcpt_Sra.
DR   Pfam; PF02117; 7TM_GPCR_Sra; 1.
DR   PRINTS; PR00697; TMPROTEINSRA.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..339
FT                   /note="Serpentine receptor class alpha-22"
FT                   /id="PRO_0000104484"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        110..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        199..219
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        250..270
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        284..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   339 AA;  38502 MW;  CA211318BD7BB45A CRC64;
     MNKTAEDLLD SLKCASKDLS SALTSVTIKF NCIFISTIVL ISYCFILLAI QALLRHNIFS
     NSTRLILIVC LLNSVVHQTT MMETRVRQIY RSFLFASDPC KLLYRSSDCV VDLYFFFLTG
     YFSTYSVFSL TSDRLVSHYK SKFYHTHQYF IAISLLVIQL LLTLVSFYIA FYGVSLAGYV
     SVCIQYPKAA VQYGTINTVR TMVMVCCLIV TGFTYYLSVK SEKQIQKISY SPGERYSAYE
     NITTSQSVCI FIILQLSCVM LTSIGMNLLL MMGEAMSEGT FTTIALFLPG ITYANLCLPL
     VIYFKTKLTI RNRKFRIAVM TSMYGDAGEH IARLKKSWE