SRC2_SOYBN
ID SRC2_SOYBN Reviewed; 290 AA.
AC O04133; I1MGQ0;
DT 14-OCT-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1997, sequence version 1.
DT 25-MAY-2022, entry version 70.
DE RecName: Full=Protein SRC2 {ECO:0000305};
DE AltName: Full=Protein SOYBEAN GENE REGULATED BY COLD 2 {ECO:0000303|Ref.1};
GN Name=SRC2 {ECO:0000303|Ref.1};
GN OrderedLocusNames=Glyma15g16360 {ECO:0000305};
OS Glycine max (Soybean) (Glycine hispida).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Glycine;
OC Glycine subgen. Soja.
OX NCBI_TaxID=3847;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND INDUCTION BY COLD STRESS.
RC STRAIN=cv. Kitamusume; TISSUE=Leaf;
RX DOI=10.1016/S0168-9452(96)04568-2;
RA Takahashi R., Shimosaka E.;
RT "cDNA sequence analysis and expression of two cold-regulated genes in
RT soybean.";
RL Plant Sci. 123:93-104(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Williams 82;
RX PubMed=20075913; DOI=10.1038/nature08670;
RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W.,
RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., May G.D.,
RA Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., Sandhu D.,
RA Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., Goodstein D.,
RA Barry K., Futrell-Griggs M., Abernathy B., Du J., Tian Z., Zhu L., Gill N.,
RA Joshi T., Libault M., Sethuraman A., Zhang X.-C., Shinozaki K.,
RA Nguyen H.T., Wing R.A., Cregan P., Specht J., Grimwood J., Rokhsar D.,
RA Stacey G., Shoemaker R.C., Jackson S.A.;
RT "Genome sequence of the palaeopolyploid soybean.";
RL Nature 463:178-183(2010).
CC -!- FUNCTION: May play a role in cold responses.
CC {ECO:0000250|UniProtKB:O04023}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000250|UniProtKB:O04023}; Single-pass type II membrane protein
CC {ECO:0000255}. Protein storage vacuole membrane
CC {ECO:0000250|UniProtKB:O04023}; Single-pass type II membrane protein
CC {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:O04023}; Single-
CC pass type II membrane protein {ECO:0000255}. Note=Moves from the ER to
CC vacuoles. {ECO:0000250|UniProtKB:O04023}.
CC -!- INDUCTION: By cold stress. {ECO:0000269|Ref.1}.
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DR EMBL; AB000130; BAA19769.1; -; mRNA.
DR EMBL; CM000848; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; T07080; T07080.
DR RefSeq; NP_001236659.1; NM_001249730.1.
DR AlphaFoldDB; O04133; -.
DR SMR; O04133; -.
DR STRING; 3847.GLYMA15G16360.1; -.
DR GeneID; 547451; -.
DR KEGG; gmx:547451; -.
DR eggNOG; ENOG502QUNY; Eukaryota.
DR OrthoDB; 1277586at2759; -.
DR Proteomes; UP000008827; Unplaced.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032586; C:protein storage vacuole membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR CDD; cd04051; C2_SRC2_like; 1.
DR Gene3D; 2.60.40.150; -; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR044750; C2_SRC2/BAP.
DR Pfam; PF00168; C2; 1.
DR SMART; SM00239; C2; 1.
DR SUPFAM; SSF49562; SSF49562; 1.
DR PROSITE; PS50004; C2; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Endoplasmic reticulum; Membrane; Reference proteome;
KW Signal-anchor; Stress response; Transmembrane; Transmembrane helix;
KW Vacuole.
FT CHAIN 1..290
FT /note="Protein SRC2"
FT /id="PRO_0000433974"
FT TOPO_DOM 1..245
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250|UniProtKB:O04023"
FT TRANSMEM 246..268
FT /note="Helical; Signal-anchor"
FT /evidence="ECO:0000255"
FT TOPO_DOM 269..290
FT /note="Lumenal"
FT /evidence="ECO:0000250|UniProtKB:O04023"
FT DOMAIN 1..114
FT /note="C2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00041"
FT REGION 167..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 290 AA; 31011 MW; 69BD35F5FD68CC1F CRC64;
MTMEYRTLEL NIISAKDIKN VNLFSKMDVY AAVSLSGDPL HPQGATTHVH KDAGSNPTWN
YPVKFSVNES LAKENRLSLE IKLISDRTLG DTVIGTVHVP LRELLDNPGD DSSFRQVSYQ
VMKQSRKSKG SLNFSYKFGE HVPAPAAKTP KAAKAGQEPV MAYPPAGAGS SSMPYGTPHP
PPPQQYAATG YGYPPQQVHG GYPPQAAYGY PPQTGYGYPQ QSGYGYPQQS GYGYPPQAQK
PKKNKFGMGL GAGLLGGALG GMLIGDMVSD AAEYDAGYDA GFDDAGGFDF
