ID   SRD2_CAEEL              Reviewed;         362 AA.
AC   Q21767;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   22-SEP-2009, sequence version 2.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Serpentine receptor class delta-2;
DE            Short=Protein srd-2;
GN   Name=srd-2; ORFNames=R05H5.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [2]
RP   FUNCTION.
RX   PubMed=7585938; DOI=10.1016/0092-8674(95)90162-0;
RA   Troemel E.R., Chou J.H., Dwyer N.D., Colbert H.A., Bargmann C.I.;
RT   "Divergent seven transmembrane receptors are candidate chemosensory
RT   receptors in C. elegans.";
RL   Cell 83:207-218(1995).
CC   -!- FUNCTION: Thought to be a chemosensory receptor.
CC       {ECO:0000269|PubMed:7585938}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the nematode receptor-like protein srd family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; Z48795; CAA88731.2; -; Genomic_DNA.
DR   PIR; T23944; T23944.
DR   RefSeq; NP_496196.2; NM_063795.2.
DR   AlphaFoldDB; Q21767; -.
DR   PaxDb; Q21767; -.
DR   EnsemblMetazoa; R05H5.1.1; R05H5.1.1; WBGene00005080.
DR   GeneID; 191795; -.
DR   KEGG; cel:CELE_R05H5.1; -.
DR   UCSC; R05H5.1; c. elegans.
DR   CTD; 191795; -.
DR   WormBase; R05H5.1; CE43249; WBGene00005080; srd-2.
DR   eggNOG; ENOG502TGQW; Eukaryota.
DR   GeneTree; ENSGT00970000195825; -.
DR   HOGENOM; CLU_057924_3_0_1; -.
DR   InParanoid; Q21767; -.
DR   OMA; CAILYFR; -.
DR   OrthoDB; 1163125at2759; -.
DR   PhylomeDB; Q21767; -.
DR   PRO; PR:Q21767; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR019421; 7TM_GPCR_serpentine_rcpt_Srd.
DR   Pfam; PF10317; 7TM_GPCR_Srd; 1.
PE   3: Inferred from homology;
KW   Membrane; Receptor; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..362
FT                   /note="Serpentine receptor class delta-2"
FT                   /id="PRO_0000104509"
FT   TRANSMEM        27..47
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        144..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        209..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        264..284
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        292..312
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   362 AA;  41041 MW;  64FB92E38A097227 CRC64;
     MNNTIQNSTI TDDLKYVMTL DKLTEYLSCL ICLPGALCNA ILIYLIWKRT PIQMRSYAIY
     ILNFALFDFA TCIISFFSCQ QVIFSDFSLV YIFHGPCKYV SPWFCYFCHC FMCHALAHSQ
     WILLGSFIYR YRVLTGETPT AKDLIRNSVA LYSMSLCFLL VYVFDNSDSD LLFQILTRVH
     PEYHYDDESI WKKSIVVSGN ISAFAPITLI SILYMTIPCV PIYCAILYFR HNTRVILNNP
     HINLSPTAKS NHVKLIRALT VQAGIPIFWL VASGIFTMSQ FGIIGGPIPE NITFRLMDCI
     PLISPIVTII FVQPYREGLL KVLLKNSGLF VPNIIGSSIV DQTVAVTSVF GPKVTAFVQT
     QL