ID   ABHDB_DANRE             Reviewed;         317 AA.
AC   Q6DRD9; A3KNU8;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Protein ABHD11 {ECO:0000305};
DE            EC=3.-.-.-;
DE   AltName: Full=Alpha/beta hydrolase domain-containing protein 11 {ECO:0000305};
DE            Short=Abhydrolase domain-containing protein 11 {ECO:0000250|UniProtKB:Q8NFV4};
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 21 protein homolog;
GN   Name=abhd11 {ECO:0000250|UniProtKB:Q8NFV4}; Synonyms=wbscr21;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RX   PubMed=15256591; DOI=10.1073/pnas.0403929101;
RA   Amsterdam A., Nissen R.M., Sun Z., Swindell E.C., Farrington S.,
RA   Hopkins N.;
RT   "Identification of 315 genes essential for early zebrafish development.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:12792-12797(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. {ECO:0000305}.
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DR   EMBL; AY648820; AAT68138.1; -; mRNA.
DR   EMBL; BC134019; AAI34020.1; -; mRNA.
DR   RefSeq; NP_001004290.1; NM_001004290.2.
DR   AlphaFoldDB; Q6DRD9; -.
DR   SMR; Q6DRD9; -.
DR   STRING; 7955.ENSDARP00000091982; -.
DR   ESTHER; danre-q6drd9; ABHD11-Acetyl_transferase.
DR   PaxDb; Q6DRD9; -.
DR   Ensembl; ENSDART00000101208; ENSDARP00000091982; ENSDARG00000069501.
DR   GeneID; 446169; -.
DR   KEGG; dre:446169; -.
DR   CTD; 83451; -.
DR   ZFIN; ZDB-GENE-040909-1; abhd11.
DR   eggNOG; KOG2382; Eukaryota.
DR   GeneTree; ENSGT00390000015880; -.
DR   HOGENOM; CLU_020336_53_0_1; -.
DR   InParanoid; Q6DRD9; -.
DR   OMA; MMYFARK; -.
DR   OrthoDB; 1268438at2759; -.
DR   PhylomeDB; Q6DRD9; -.
DR   TreeFam; TF314071; -.
DR   PRO; PR:Q6DRD9; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 21.
DR   Bgee; ENSDARG00000069501; Expressed in brain and 20 other tissues.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; IBA:GO_Central.
DR   GO; GO:0044255; P:cellular lipid metabolic process; IBA:GO_Central.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   PRINTS; PR00111; ABHYDROLASE.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..317
FT                   /note="Protein ABHD11"
FT                   /id="PRO_0000281005"
FT   DOMAIN          69..304
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000255"
FT   ACT_SITE        142
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        238
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        297
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   317 AA;  34924 MW;  3F58F22D6342AF6D CRC64;
     MSNFAMSALC RVFTRGAPCG LSSCSSVTGL RDFCSGVSRL DRAGSDSMRT ASPVNLTYDV
     FDGKGDSTPL VFLHGLFGSK SNFHSIAKSL VQRTGRKVLT IDARNHGKSP HSPVLTYDTM
     TSDLTHLLGQ LHIGKCVLIG HSMGGKVAMT TALSQPNLVE RLVVVDISPS LTSAHTNFHA
     YIQAMKEVKI PSDIPRSTAR RLAEDQLRKI VKERSVRQFL LTNLEEQNGQ YGWRINLESI
     SNHLEDILGF PEFDTTYEGP TLFLGGSSSA YISSDDYPEI QRLFPCADIQ YIPDASHWIH
     ADKPLDFISS IITFLQP