ID   SRE12_CAEEL             Reviewed;         341 AA.
AC   O61898;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Serpentine receptor class epsilon-12;
DE            Short=Protein sre-12;
GN   Name=sre-12; ORFNames=T07H8.7;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the nematode receptor-like protein sre family.
CC       {ECO:0000305}.
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DR   EMBL; FO080767; CCD66562.1; -; Genomic_DNA.
DR   PIR; T33221; T33221.
DR   RefSeq; NP_504764.1; NM_072363.1.
DR   AlphaFoldDB; O61898; -.
DR   STRING; 6239.T07H8.7; -.
DR   PaxDb; O61898; -.
DR   EnsemblMetazoa; T07H8.7.1; T07H8.7.1; WBGene00020333.
DR   GeneID; 188261; -.
DR   KEGG; cel:CELE_T07H8.7; -.
DR   UCSC; T07H8.7; c. elegans.
DR   CTD; 188261; -.
DR   WormBase; T07H8.7; CE18228; WBGene00020333; sre-12.
DR   eggNOG; ENOG502RVP7; Eukaryota.
DR   GeneTree; ENSGT00970000196776; -.
DR   HOGENOM; CLU_043866_1_0_1; -.
DR   InParanoid; O61898; -.
DR   OMA; SAKQFHY; -.
DR   OrthoDB; 1381038at2759; -.
DR   PhylomeDB; O61898; -.
DR   PRO; PR:O61898; -.
DR   Proteomes; UP000001940; Chromosome V.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007606; P:sensory perception of chemical stimulus; IEA:InterPro.
DR   InterPro; IPR004151; 7TM_GPCR_serpentine_rcpt_Sre.
DR   Pfam; PF03125; Sre; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..341
FT                   /note="Serpentine receptor class epsilon-12"
FT                   /id="PRO_0000104538"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        140..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        167..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        230..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        262..282
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   341 AA;  39706 MW;  0CD09F802D5815D5 CRC64;
     MLLLHYFNLS HFQVNDHFYP HMRNFLYGET AFYVADTINM MFYIWVLFSA QQFHFNFTLV
     SGTQYVIHFF DNLAIIVMRL HSLLGFTDDF DIGSNVVFNG AMTFSVYCIV AAMCSLPFSI
     LERCFATRYL KDYEANSRAY ISYALVFLLN FIGIIGAILL QNKNNTIFVV AFLMILNLFA
     LLTNQFLRTW NLKKYEECHS NVSIRFQRGG KYSLAKRFQI SENIKSLHML NFIILYMGFM
     NVCLVISVLF SSFDISPERQ AICSLALDAS IFFYSFAIPQ IMTCFCHKWK VQTNTFRIRI
     GCLRTGKVNL EPLRDTFGGD MRGSVSMNRY FDQLQDSWEN A