ID   SRE45_CAEEL             Reviewed;         369 AA.
AC   O02275;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 3.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Serpentine receptor class epsilon-45;
DE            Short=Protein sre-45;
GN   Name=sre-45; ORFNames=F54F11.3;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the nematode receptor-like protein sre family.
CC       {ECO:0000305}.
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DR   EMBL; Z83229; CAB05740.3; -; Genomic_DNA.
DR   PIR; T22669; T22669.
DR   RefSeq; NP_496843.2; NM_064442.2.
DR   AlphaFoldDB; O02275; -.
DR   STRING; 6239.F54F11.3; -.
DR   PaxDb; O02275; -.
DR   EnsemblMetazoa; F54F11.3.1; F54F11.3.1; WBGene00010071.
DR   GeneID; 186258; -.
DR   KEGG; cel:CELE_F54F11.3; -.
DR   UCSC; F54F11.3; c. elegans.
DR   CTD; 186258; -.
DR   WormBase; F54F11.3; CE32897; WBGene00010071; sre-45.
DR   eggNOG; KOG0789; Eukaryota.
DR   GeneTree; ENSGT00970000195947; -.
DR   HOGENOM; CLU_063305_1_0_1; -.
DR   InParanoid; O02275; -.
DR   OMA; GGFIKWH; -.
DR   OrthoDB; 1257903at2759; -.
DR   PhylomeDB; O02275; -.
DR   PRO; PR:O02275; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007606; P:sensory perception of chemical stimulus; IEA:InterPro.
DR   InterPro; IPR004151; 7TM_GPCR_serpentine_rcpt_Sre.
DR   Pfam; PF03125; Sre; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..369
FT                   /note="Serpentine receptor class epsilon-45"
FT                   /id="PRO_0000104550"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        127..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        169..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        195..217
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        258..278
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        291..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   369 AA;  42428 MW;  2B6FBE685DA03759 CRC64;
     MIFLIGNSTS NYTVCFPIFI LEDTRALKFP YSMLQALEFV LTFVSFYYVI KCCYVAIHIK
     SFHRNLTVLL IILMIQWFEG LLSNILIKPY ETGFWPLGEH NTQLKQWWTK DYSKMIQVPN
     LSTFPNFFLG GFLKWHYILS MITTLLVMSI ERSFACYFLT DYEKKSRNGL FFMLVVGQTS
     TNLVMGYLFF FNAAHFAVGF SIILSTNIIA MGIFTYVKHV NRQVNRAIED FSNPSLYCLP
     ARFQVRENVR CFQMITKVIH AGLFLILTAC FVNLFMYLEL TPGLDPLLNL IFESAINLNP
     VVIVPTLLGS VNAWRNFTFS SGVCLGFKAQ VRLKIIKVSS VSIGNDGAKS DRTRKETDAY
     FDQLNSAWI