ID   SRE8_CAEEL              Reviewed;         341 AA.
AC   Q20249;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Serpentine receptor class epsilon-8;
DE            Short=Protein sre-8;
GN   Name=sre-8; ORFNames=F40G12.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the nematode receptor-like protein sre family.
CC       {ECO:0000305}.
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DR   EMBL; Z77661; CAB01186.1; -; Genomic_DNA.
DR   PIR; T22057; T22057.
DR   RefSeq; NP_506528.1; NM_074127.1.
DR   AlphaFoldDB; Q20249; -.
DR   SMR; Q20249; -.
DR   PaxDb; Q20249; -.
DR   EnsemblMetazoa; F40G12.1.1; F40G12.1.1; WBGene00009596.
DR   GeneID; 185561; -.
DR   KEGG; cel:CELE_F40G12.1; -.
DR   UCSC; F40G12.1; c. elegans.
DR   CTD; 185561; -.
DR   WormBase; F40G12.1; CE10176; WBGene00009596; sre-8.
DR   eggNOG; ENOG502TCXE; Eukaryota.
DR   GeneTree; ENSGT00970000196776; -.
DR   HOGENOM; CLU_043866_1_1_1; -.
DR   InParanoid; Q20249; -.
DR   OMA; YSALPEW; -.
DR   OrthoDB; 996807at2759; -.
DR   PhylomeDB; Q20249; -.
DR   PRO; PR:Q20249; -.
DR   Proteomes; UP000001940; Chromosome V.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007606; P:sensory perception of chemical stimulus; IEA:InterPro.
DR   InterPro; IPR004151; 7TM_GPCR_serpentine_rcpt_Sre.
DR   Pfam; PF03125; Sre; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..341
FT                   /note="Serpentine receptor class epsilon-8"
FT                   /id="PRO_0000104537"
FT   TRANSMEM        37..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        64..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        101..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        143..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        169..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        235..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        264..284
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   341 AA;  40187 MW;  33A47F63046DFC3D CRC64;
     MCSPSTSDVR FITFVNTTYI EAEGLEAIFD LLLKIEVGFL VFSWIEFLYL FYLFIFIRSM
     HFNLTFLFMN YGGQYFCSML SRCIIVYQQL GNDPNNDLHN WILVANFART VCLFIAMYIL
     PIFMIERCLA SFFVKNYEKS RKIWVSLMIL SIFHPLVFAS AIAYIQCWIP VVVHVISFFI
     VNIIGYIGIH ICYSYNIKKH RKFYSPQCIS RVTYGLSERF QLAENIKMCK VLKKVQISIL
     FFNIGCCSIL LMDHFQVKMM IIYWSYVCFN FFALVYGITV PIILYSALPE WQKETRRLLN
     LCIGRRNVGE EPKSTFGEQM IYNDHAIESN IYFTQFNKTT H