SRG20_CAEEL
ID SRG20_CAEEL Reviewed; 346 AA.
AC P91535; Q5DX28;
DT 25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT 19-SEP-2006, sequence version 4.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=Serpentine receptor class gamma-20;
DE Short=Protein srg-20;
GN Name=srg-20; ORFNames=ZC204.4;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=b;
CC IsoId=P91535-1; Sequence=Displayed;
CC Name=a;
CC IsoId=P91535-2; Sequence=VSP_020532;
CC -!- SIMILARITY: Belongs to the nematode receptor-like protein srg family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FO080436; CCD63684.1; -; Genomic_DNA.
DR EMBL; FO080436; CCD63685.1; -; Genomic_DNA.
DR PIR; T25950; T25950.
DR RefSeq; NP_001022490.1; NM_001027319.2. [P91535-2]
DR RefSeq; NP_001022491.1; NM_001027320.1. [P91535-1]
DR AlphaFoldDB; P91535; -.
DR SMR; P91535; -.
DR PaxDb; P91535; -.
DR EnsemblMetazoa; ZC204.4a.1; ZC204.4a.1; WBGene00005177. [P91535-2]
DR EnsemblMetazoa; ZC204.4b.1; ZC204.4b.1; WBGene00005177. [P91535-1]
DR GeneID; 191110; -.
DR KEGG; cel:CELE_ZC204.4; -.
DR UCSC; ZC204.4a; c. elegans. [P91535-1]
DR CTD; 191110; -.
DR WormBase; ZC204.4a; CE36350; WBGene00005177; srg-20. [P91535-2]
DR WormBase; ZC204.4b; CE33252; WBGene00005177; srg-20. [P91535-1]
DR eggNOG; ENOG502TGR1; Eukaryota.
DR GeneTree; ENSGT00970000195841; -.
DR InParanoid; P91535; -.
DR PhylomeDB; P91535; -.
DR PRO; PR:P91535; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00005177; Expressed in embryo.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0007606; P:sensory perception of chemical stimulus; IEA:InterPro.
DR InterPro; IPR000609; 7TM_GPCR_serpentine_rcpt_Srg.
DR Pfam; PF02118; Srg; 1.
DR PRINTS; PR00698; TMPROTEINSRG.
PE 3: Inferred from homology;
KW Alternative splicing; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..346
FT /note="Serpentine receptor class gamma-20"
FT /id="PRO_0000104567"
FT TRANSMEM 27..47
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 106..128
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 212..232
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 254..274
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 279..299
FT /note="Helical"
FT /evidence="ECO:0000255"
FT VAR_SEQ 319..346
FT /note="GFTKFPVILVEMISDSSPHLLIINLQLV -> LSASSHNQPAARVMAPVMH
FT (in isoform a)"
FT /evidence="ECO:0000305"
FT /id="VSP_020532"
SQ SEQUENCE 346 AA; 39548 MW; FE75A7916E4F16D2 CRC64;
MSTRLIIPAN FSYDDPLPFT CNQDSHVMLS ILEYLVQATY LSVSAVLNSM IVYTIFRCKG
KHSYRRNPFF VLYAAEAVMN VYSCVIEVLF GRLIIYMTPL CPALSPFFFT PSILTKLYFL
LNHYCLAFKT LSQIAISFNR MTCVIFPVHH FKLWQNILAP VLVSLFVLPL GVTWNILVSR
VYVNPNGAGF SVNYRDAVAW ANISFLHLFH CIPCLFLMIV FFLASIFGLT MLENRLRSAE
RSLIIFTMTL GVETMLFAIA QIYFAFLAGY LPGIRPLMLL ISFNVFDVLY VYSPIALILM
NRQLRRDIFH LKGDDPGFGF TKFPVILVEM ISDSSPHLLI INLQLV